Searching journal content for articles similar to van Arensbergen et al. 20 (6): 722.

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  1. Research: Functional genomics analysis of developing zebrafish and human endoderm reveals highly conserved cis-regulatory modules acting during vertebrate organogenesis
    • Daniela M Riley,
    • Randa Elsayed,
    • Mark D Walsh,
    • Simaran Johal,
    • Ying Lin,
    • Harry Walton,
    • Till Bretschneider,
    • Sascha Ott,
    • and Andrew C Nelson
    Genome Res. March 4, 2026 gr.280838.125; Published in Advance March 4, 2026, doi:10.1101/gr.280838.125
    ...However, rigid arrangement of binding sites is not a common characteristic of the identified 40 CRMs, suggesting more complex or individual grammatical rules. Overall, our analyses 41 provide key insights into critical gene regulatory control during vertebrate endoderm 42 organogenesis, and define...
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  2. Research: Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation
    • Lieven Thorrez,
    • Ilaria Laudadio,
    • Katrijn Van Deun,
    • Roel Quintens,
    • Nico Hendrickx,
    • Mikaela Granvik,
    • Katleen Lemaire,
    • Anica Schraenen,
    • Leentje Van Lommel,
    • Stefan Lehnert,
    • Cristina Aguayo-Mazzucato,
    • Rui Cheng-Xue,
    • Patrick Gilon,
    • Iven Van Mechelen,
    • Susan Bonner-Weir,
    • Frédéric Lemaigre,
    • and Frans Schuit
    Genome Res. January 2011 21: 95-105; Published in Advance November 18, 2010, doi:10.1101/gr.109173.110
    ...in the differentiated cell. Chromatin condensation and the resulting gene silencing play a key role in differentiation. A hallmark for transcriptional silencing is trimethylation of lysine27 on histone H3 (H3K27me3), a process that is catalyzed by the methyl transferase activity of the Polycomb complex PCR2 (Vire et al...
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