Searching journal content for articles similar to de Wit et al. 19 (11): 2064.

Displaying results 1-10 of 12

For checked items

view abstracts
download to citation manager

Select this article
Research: Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus
- Jaaved Mohammed,
- Alex S. Flynt,
- Alexandra M. Panzarino,
- Md Mosharrof Hossain Mondal,
- Matthew DeCruz,
- Adam Siepel,
- and Eric C. Lai
Genome Res. January 2018 28: 52-65; Published in Advance December 12, 2017, doi:10.1101/gr.226068.117
..., University of Southern Mississippi, Hattiesburg, Mississippi 39406, USA ↵6 These authors contributed equally to this work. Corresponding author: laie@mskcc.orgAbstractTo assess miRNA evolution across the Drosophila genus, we analyzed several billion small RNA reads across 12 fruit fly species. These data...
Select this article
Method: Scaffolding a Caenorhabditis nematode genome with RNA-seq
- Ali Mortazavi,
- Erich M. Schwarz,
- Brian Williams,
- Lorian Schaeffer,
- Igor Antoshechkin,
- Barbara J. Wold,
- and Paul W. Sternberg
Genome Res. December 2010 20: 1740-1747; Published in Advance October 27, 2010, doi:10.1101/gr.111021.110
...to a slr-2/jmjc-1-dependent stress-response motif conserved between ecdysozoa and deuterostomes (Fig. 5B; Kirienko and Fay 2010). Other predicted motifs matched a miRNA promoter-associated motif (Ohler et al. 2004), the core promoter SP1 site (Li et al. 2004), muscle-specific motifs 1–4 of Zhao et al...
Select this article
Research: High-throughput sequencing reveals extraordinary fluidity of miRNA, piRNA, and siRNA pathways in nematodes
- Zhen Shi,
- Taiowa A. Montgomery,
- Yan Qi,
- and Gary Ruvkun
Genome Res. March 2013 23: 497-508; Published in Advance January 30, 2013, doi:10.1101/gr.149112.112
...The nematode Caenorhabditis elegans contains each of the broad classes of eukaryotic small RNAs, including microRNAs (miRNAs), endogenous small-interfering RNAs (endo-siRNAs), and piwi-interacting RNAs (piRNAs). To better understand the evolution of these regulatory RNAs, we deep-sequenced small RNAs from C...
Select this article
Research: Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles
- Jianbin Wang,
- Benjamin Czech,
- Amanda Crunk,
- Adam Wallace,
- Makedonka Mitreva,
- Gregory J. Hannon,
- and Richard E. Davis
Genome Res. September 2011 21: 1462-1477; Published in Advance June 17, 2011, doi:10.1101/gr.121426.111
...conservation and divergence of nematode miRNAs over 400 million years of evolution. Ascaris endo-siRNAs (26G- and 22G-RNAs), particularly in the testis, demonstrate striking adaptability and plasticity in their expression and biogenesis, including the loss of 39 29-Omethylation of small RNAs, when comparedwith...
Select this article
Research: Contributions of mRNA abundance, ribosome loading, and post- or peri-translational effects to temporal repression of C. elegans heterochronic miRNA targets
- Michael Stadler,
- Karen Artiles,
- Julia Pak,
- and Andrew Fire
Genome Res. December 2012 22: 2418-2426; Published in Advance August 1, 2012, doi:10.1101/gr.136515.111
...made characterizing miRNA repertoires and elucidating their physiological roles, the molecular mechanism(s) by which miRNAs (and their effector proteins) reduce protein output of target genes have remained controversial. Initial analysis of the C. elegans miRNAs lin-4 and let-7 indicated that miRNAs...
Select this article
Research: Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgression
- Runsheng Li,
- Xiaoliang Ren,
- Yu Bi,
- Vincy Wing Sze Ho,
- Chia-Ling Hsieh,
- Amanda Young,
- Zhihong Zhang,
- Tingting Lin,
- Yanmei Zhao,
- Long Miao,
- Peter Sarkies,
- and Zhongying Zhao
Genome Res. September 2016 26: 1219-1232; Published in Advance May 18, 2016, doi:10.1101/gr.204479.116
...appreciable sequence divergence (Fig. 7E). Thus it is possible that a sequence difference in the promoter of mir-237 might drive the differential expression of this miRNA in both C. briggsae and C. nigoni background. The differential expression we observed may contribute to the sterility of hybrid lines...
Select this article
Research: Cnidarian microRNAs frequently regulate targets by cleavage
- Yehu Moran,
- David Fredman,
- Daniela Praher,
- Xin Z. Li,
- Liang Meng Wee,
- Fabian Rentzsch,
- Phillip D. Zamore,
- Ulrich Technau,
- and Hervé Seitz
Genome Res. April 2014 24: 651-663; Published in Advance March 18, 2014, doi:10.1101/gr.162503.113
...miRNA “seed”) to the target, subsequently promoting translational inhibition and transcript instability. In plants, many miRNAs guide endonucleolytic cleavage of highly complementary targets. Because little is known about miRNA function in nonbilaterian animals, we investigated the repertoire...
OPEN ACCESS ARTICLE
Select this article
ARTICLE: Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression
- Wei Deng,
- Xiaopeng Zhu,
- Geir Skogerbø,
- Yi Zhao,
- Zhuo Fu,
- Yudong Wang,
- Housheng He,
- Lun Cai,
- Hong Sun,
- Changning Liu,
- Biao Li,
- Baoyan Bai,
- Jie Wang,
- Dong Jia,
- Shiwei Sun,
- Hang He,
- Yan Cui,
- Yu Wang,
- Dongbo Bu,
- and Runsheng Chen
Genome Res. January 2006 16: 20-29; Published in Advance December 12, 2005, doi:10.1101/gr.4139206
...acting as regulatory elements in nematode development. Small non-protein-coding RNAs (ncRNAs) such as microRNAs (miRNAs) have received increasing attention as regulatory factors shaping cellular and organismal life. A catalog of reported miRNAs from various eukaryotes now covers 400 different RNA species...
Select this article
Research: Global regulatory features of alternative splicing across tissues and within the nervous system of C. elegans
- Bina Koterniak,
- Pallavi P. Pilaka,
- Xicotencatl Gracida,
- Lisa-Marie Schneider,
- Iva Pritišanac,
- Yun Zhang,
- and John A. Calarco
Genome Res. December 2020 30: 1766-1780; Published in Advance October 30, 2020, doi:10.1101/gr.267328.120
..., a significant fraction of multiexon genes undergo alternative splicing, with higher frequencies reported across vertebrates (Pan et al. 2008; Wang et al. 2008; Barbosa-Morais et al. 2012; Merkin et al. 2012) in comparison to invertebrate model organisms such as the nematode Caenorhabditis elegans and the fruit...
OPEN ACCESS ARTICLE
Select this article
Method: Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans
- Wei-Jen Chung,
- Phaedra Agius,
- Jakub O. Westholm,
- Michael Chen,
- Katsutomo Okamura,
- Nicolas Robine,
- Christina S. Leslie,
- and Eric C. Lai
Genome Res. February 2011 21: 286-300; Published in Advance December 22, 2010, doi:10.1101/gr.113050.110
...by several orders of magnitude. Consequently, the most successful methods for computational miRNA gene finding rely upon evolutionary conservation of miRNA candidates (Grad et al. 2003; Lai et al. 2003; Lim et al. 2003a,b). In particular, conserved hairpins that diverge more quickly in their terminal loops...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to de Wit et al. 19 (11): 2064.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: