Searching journal content for articles similar to de Chaldée et al. 13 (7): 1646.

Displaying results 1-10 of 14

For checked items

view abstracts
download to citation manager

Select this article
Review: Artificial intelligence and machine learning in cell-free-DNA-based diagnostics
- W.H. Adrian Tsui,
- Spencer C. Ding,
- Peiyong Jiang,
- and Y.M. Dennis Lo
Genome Res. January 2025 35: 1-19; doi:10.1101/gr.278413.123
...truly intelligent behavior (Wooldridge 2021). The explosive increase of computational power in the twenty-first century enabled deep learning, which uses “deep” neural networks (DNNs), to be applied widely (Hoffmann 2022). Because of the analogies to neuronal mechanics in the brain, deep learning is now...
OPEN ACCESS ARTICLE
Select this article
Method: Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin
- Kun Sun,
- Peiyong Jiang,
- Suk Hang Cheng,
- Timothy H.T. Cheng,
- John Wong,
- Vincent W.S. Wong,
- Simon S.M. Ng,
- Brigette B.Y. Ma,
- Tak Y. Leung,
- Stephen L. Chan,
- Tony S.K. Mok,
- Paul B.S. Lai,
- Henry L.Y. Chan,
- Hao Sun,
- K.C. Allen Chan,
- Rossa W.K. Chiu,
- and Y.M. Dennis Lo
Genome Res. March 2019 29: 418-427; Published in Advance February 26, 2019, doi:10.1101/gr.242719.118
...plasma (Chim et al. 2005). More recently, a similar approach has been applied to the detection of cfDNA derived from the brain (Lehmann-Werman et al. 2016), cells of the erythroid lineage (Lam et al. 2017), the heart (Zemmour et al. 2018), and the liver (Gai et al. 2018; Lehmann-Werman et al. 2018).We...
OPEN ACCESS ARTICLE
Select this article
Research: Transcriptional regulatory dynamics drive coordinated metabolic and neural response to social challenge in mice
- Michael C. Saul,
- Christopher H. Seward,
- Joseph M. Troy,
- Huimin Zhang,
- Laura G. Sloofman,
- Xiaochen Lu,
- Patricia A. Weisner,
- Derek Caetano-Anolles,
- Hao Sun,
- Sihai Dave Zhao,
- Sriram Chandrasekaran,
- Saurabh Sinha,
- and Lisa Stubbs
Genome Res. June 2017 27: 959-972; Published in Advance March 29, 2017, doi:10.1101/gr.214221.116
...expression and chromatin modulation in the mouse brain as animals respond to a salient social challenge in the form of a territorial threat. It is well known that threatened animals adjust their behavior after exposure to such a challenge (Fernald and Maruska 2012), and our goal was to develop a novel view...
Select this article
Research: An iPSC-based model of 47,XYY Jacobs syndrome reveals a DNA methylation-independent transcriptional dysregulation shared with male X aneuploid cells
- Veronica Astro,
- Kelly Yojanna Cardona-Londoño,
- Lorena Viridiana Cortés-Medina,
- Rawan Alghamdi,
- Gustavo Ramírez-Calderón,
- Fotios Kefalas,
- Jair Dilmé-Capó,
- Santiago Radío,
- and Antonio Adamo
Genome Res. July 2025 35: 1503-1517; Published in Advance June 10, 2025, doi:10.1101/gr.279716.124
...used a dual approach: a simulation of Y Chromosome transcriptome RNA-seq reads and multimapping assessment on iPSC transcriptomic data (Supplemental Data S12; Supplemental Materials).We divided the adjusted count matrix per cell type to independently perform the gene filtering and DEA. Genes with low...
OPEN ACCESS ARTICLE
Select this article
Research: Unexpectedly low recombination rates and presence of hotspots in termite genomes
- Turid Everitt,
- Tilman Rönneburg,
- Daniel Elsner,
- Anna Olsson,
- Yuanzhen Liu,
- Tuuli Larva,
- Judith Korb,
- and Matthew T. Webster
Genome Res. May 2025 35: 1124-1137; Published in Advance March 20, 2025, doi:10.1101/gr.279180.124
.... The robustness of the association between eusociality and high recombination rates can therefore be addressed by assessing mean genomic recombination rates in social Blattodea (termites).In addition to variation between species, the rate of recombination also varies along chromosomes. In mammals, crossover...
Select this article
Research: Genomic insights into metabolic flux in hummingbirds
- Ariel Gershman,
- Quinn Hauck,
- Morag Dick,
- Jerrica M. Jamison,
- Michael Tassia,
- Xabier Agirrezabala,
- Saad Muhammad,
- Raafay Ali,
- Rachael E. Workman,
- Mikel Valle,
- G. William Wong,
- Kenneth C. Welch, Jr.,
- and Winston Timp
Genome Res. May 2023 33: 703-714; Published in Advance May 8, 2023, doi:10.1101/gr.276779.122
...control of orthologous pathways in humans.ResultsChromosome-level assemblyUsing hummingbird brain tissue, we generated a total of 26 Gb of Nanopore sequencing data on the PromethION with a read-length N50 of 40 kb and 240 Gb of short-read Illumina NovaSeq data (Methods) (Fig. 1A). We performed hybrid...
Select this article
Resource: A new emu genome illuminates the evolution of genome configuration and nuclear architecture of avian chromosomes
- Jing Liu,
- Zongji Wang,
- Jing Li,
- Luohao Xu,
- Jiaqi Liu,
- Shaohong Feng,
- Chunxue Guo,
- Shengchan Chen,
- Zhanjun Ren,
- Jinpeng Rao,
- Kai Wei,
- Yuezhou Chen,
- Erich D. Jarvis,
- Guojie Zhang,
- and Qi Zhou
Genome Res. March 2021 31: 497-511; Published in Advance January 6, 2021, doi:10.1101/gr.271569.120
...or frameshift mutations) in S0 than in S1 on the W Chromosome. (D) The log expression levels (TPM) of single-copy homologous genes in the S0 and S1 regions of Z and W Chromosomes. (B) Brain, (EB) embryonic brain, (K) kidney, (EK) embryonic kidney, (S) spleen, (O) ovary. The genes with blue color indicate...
Select this article
Research: Positive selection in noncoding genomic regions of vocal learning birds is associated with genes implicated in vocal learning and speech functions in humans
- James A. Cahill,
- Joel Armstrong,
- Alden Deran,
- Carolyn J. Khoury,
- Benedict Paten,
- David Haussler,
- and Erich D. Jarvis
Genome Res. November 2021 31: 2035-2049; Published in Advance October 19, 2021, doi:10.1101/gr.275989.121
...to imitate sounds from conspecifics and the environment, is a key component of human spoken language and learned song in three independently evolved avian groups—oscine songbirds, parrots, and hummingbirds. Humans and each of these three bird clades exhibit specialized behavioral, neuroanatomical, and brain...
OPEN ACCESS ARTICLE
Select this article
Method: Single-cell-level spatial gene expression in the embryonic neural differentiation niche
- Yi Huang,
- Xiaoming Yu,
- Na Sun,
- Nan Qiao,
- Yaqiang Cao,
- Jerome D. Boyd-Kirkup,
- Qin Shen,
- and Jing-Dong J. Han
Genome Res. April 2015 25: 570-581; Published in Advance January 9, 2015, doi:10.1101/gr.181966.114
...expression profiles—markers of S phase and G2/M checkpoint have separated territories, with other intermediary stage markers scattered in between (Supplemental Fig. S5). A few mitotic checkpoint genes in our study have been found to affect brain size and brain development. For example,Nde1 (Cluster 1...
Select this article
Research: Divergence patterns of genic copy number variation in natural populations of the house mouse (Mus musculus domesticus) reveal three conserved genes with major population-specific expansions
- Željka Pezer,
- Bettina Harr,
- Meike Teschke,
- Hiba Babiker,
- and Diethard Tautz
Genome Res. August 2015 25: 1114-1124; Published in Advance July 6, 2015, doi:10.1101/gr.187187.114
...involved in brain function has been demonstrated to be a significant confounder when performing gene set enrichment analyses on CNVs and to cause spurious findings (Raychaudhuri et al. 2010). By performing permutations of CNVRs across the , we show that despite their relatively larger size...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to de Chaldée et al. 13 (7): 1646.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: