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  1. ...reflect type I error; in general, the observed allele frequencies predicted the observed genotype frequencies. Linkage Disequilibrium Using 1100 chromosomes from 275 families, three loci were examined for haplotypes defined by multiple sites typed within each gene: ELAM (three sites), LPL (four sites...
  2. .... This is also the first report of a protective effect on proteinuria by Agtrap, a mediator of the renin-angiotensin system (Oppermann et al. 2010). Functional annotation of the human AGTRAP-PLOD1 locus Our data show that multiple genes in the Agtrap-Plod1 locus modify BP and renal phenotypes in the SS rat (Fig...
  3. ...: 203 -214. ↵ Zhu, X., Yan, D., Cooper, R.S., Luke, A., Ikeda, M.A., Chang, Y.C., Weder, A., and Chakravarti, A. 2003 . Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: Findings from the family blood pressure program. Genome Res. 13 : 173 -181. Single...
  4. ...) the P-selectin gene and myocardial infarction, (2) the cholesteryl ester transfer protein gene and plasma high-density-lipoprotein cholesterol concentration, and (3) genes of the renin-angiotensin-aldosterone system and myocardial infarction. The applications demonstrated that the method was able...
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