Searching journal content for articles similar to Zhou et al. 30 (3): 392.

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  1. ...: mkirst@ufl.eduAbstractDespite the growing resources and tools for high-throughput characterization and analysis of genomic information, the discovery of the genetic elements that regulate complex traits remains a challenge. Systems genetics is an emerging field that aims to understand the flow...
  2. ...to be accommodated in systems genetic modeling, at least at the level of gene expression.MethodsDrosophila linesWe used 200 inbred, sequenced DGRP lines (Mackay et al. 2012; Huang et al. 2014) established by 20 generations of full sib inbreeding from gravid females collected at the Raleigh, North Carolina, Farmer...
  3. ...; Demontis et al. 2013a, 2014; Keipert et al. 2013; Stenesen et al. 2013; Rai and Demontis 2016). The progressive functional deterioration of skeletal muscle starts from an early age and precedes the age-related systemic decline in proteostasis and tissue integrity in Drosophila (Demontis and Perrimon 2010...
  4. ...), recoding is overrepresented in twomajor clades, coleoids (Cephalopoda) (Alon et al. 2015; Liscovitch-Brauer et al. 2017) and Drosophila (Insecta) (Yu et al. 2016; Yablonovitch et al. 2017a; Duan et al. 2024a). The temporospatial regulation of RNA editing circumvents the pleiotropic effects caused by DNA...
  5. ...previous studies characterizing transcriptomic (Hu et al. 2007; Kemmeren et al. 2014), metabolomic (Shakoury-Elizeh et al. 2010; Mülleder et al. 2016; Zelezniak et al. 2018), and proteomic (Messner et al. 2023) responses to genetic perturbations, the exact chromatin-mediated mechanisms enacting...
  6. ...46: D296–D302. doi:10.1093/nar/gkx1067 ↵Elizarraras JM, Liao Y, Shi Z, Zhu Q, Pico AR, Zhang B. 2024. WebGestalt 2024: faster gene set analysis and new support for metabolomics and multi-omics. Nucleic Acids Res 52: W415–W421. doi:10.1093/nar/gkae456 ↵Enright A, John B, Gaul U, Tuschl T, Sander C...
  7. ...A metabolomic and systems biology perspective on the brain of the Fragile X syndrome mouse model Laetitia Davidovic 1 , 2 , 8 , Vincent Navratil 3 , 4 , Carmela M. Bonaccorso 5 , Maria Vincenza Catania 5 , 6 , Barbara Bardoni 1 , 2...
  8. ...of systems biology, whereas others prefer not to put a label on what is happening. Modern molecular biology was born with the discovery that genetics is based on nucleic acid chemistry ( Watson and Crick 1953 ), and one way to define it is to say that molecular biology is a large box of tools to do genetics...
  9. ...the accuracy of the detection of positive selection (Grossman et al. 2010).In this study, we investigated the genomic interplay between selection and genetic drift leading to the island syndrome in a system with an exceptionally long and clear history of population isolation. Common voles (Microtus arvalis...
  10. ...SpaCeNet in extensive simulation studies and illustrate its capacity to augment exploratory data analysis of spatial transcriptomics data from the mouse visual cortex, mouse organogenesis, and the Drosophila blastoderm.ResultsSpaCeNet infers cell–cell interactions from spatial omics data...
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