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  1. ...pair range, precluding direct identification of specific sites of DNA modification. A new method based on ChIP-seq for mapping sites of singlestranded DNA enables global studies of putative DNA damage but does not identify specific modified nucleobases (Zhou et al. 2013). Finally, new single...
  2. ...of the checkpoint in this context does not give rise to origin-associated DNA damage.Finally, we evaluated the overall impact of reprogramming DNA replication on the landscape of instability. We compared the density of Rad52 hotspots over continuous 1000-probe windows in rif1Δ rad3Δ and rad3Δ cells in the absence...
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