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  1. ..., such as the joint embedding from deep learning–based methods. This could potentially enhance the performance and robustness of the consensus clustering. Second, the current version of our consensus framework only incorporates seven tools, which is relatively limited considering the vast number of clustering tools...
  2. ...benchmarked (Li et al. 2022). As examples, methods have been proposed to predict unmeasured gene expression by aggregating nearest neighbors of cells for regression (Stuart et al. 2019; Welch et al. 2019; Abdelaal et al. 2020; Shengquan et al. 2021), joint probabilistic modeling (Lopez et al. 2019; Wan et al...
  3. ...(MNN) approach has been used to align these data types, which results in cell locations mapping (Haghverdi et al. 2018; Hie et al. 2019; Stuart et al. 2019). DEEPsc uses an artificial neural network to predict spatial locations (Maseda et al. 2021). GLUER combines joint NMF, MNN algorithm, and deep...
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  4. ...cell identity information from transcriptome features solely. In scHGR, transcriptomically distant cells are bridged by homologous genes and their relationships. Attaining homotypic cell communication across species facilitates improving the reliability of cross-species annotation.View larger version...
  5. .... Joint imputation and deconvolution of gene expression across spatial transcriptomics platforms . Genome Res (this issue) 35 : 2734 – 2743 . doi: 10.1101/gr.280555.125 Genome Res GENOME Genome Research Genome Res. Genome Res 1088-9051 1549-5469 Cold Spring Harbor Laboratory Press 9509184 10.1101/gr...
  6. ...effects through explicit modeling of batch information as covariates; and CarDEC (Lakkis et al. 2021) uses a joint autoencoder together with iterative clustering to remove batch effects. Beyond the ability to model all batches simultaneously, an additional advantage of these neural network–based methods...
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