Searching journal content for articles similar to Zhang et al. 30 (4): 566.

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  1. Research: Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary
    • Satyam P. Srivastav,
    • Cédric Feschotte,
    • and Andrew G. Clark
    Genome Res. May 2024 34: 711-724; Published in Advance May 15, 2024, doi:10.1101/gr.278062.123
    ...that TEs themselves are the major force driving the rapid evolution of piCs.Animal s are parasitized by a horde of transposable elements (TEs) whose mutagenic activity can lead to sterility (Bingham et al. 1982; Bucheton et al. 1984). In the animal germline, the Piwi-interacting RNA (piRNA) pathway...
  2. Research: Cellular abundance shapes function in piRNA-guided genome defense
    • Pavol Genzor,
    • Parthena Konstantinidou,
    • Daniel Stoyko,
    • Amirhossein Manzourolajdad,
    • Celine Marlin Andrews,
    • Alexandra R. Elchert,
    • Constantinos Stathopoulos,
    • and Astrid D. Haase
    Genome Res. November 2021 31: 2058-2068; Published in Advance October 19, 2021, doi:10.1101/gr.275478.121
    ...changes in piRNA abundance affect piRNA function. To directly measure how much piRNA abundance impacts piRNA-guided silencing, we developed a reporter assay. Our design aimed at providing a quantitative readout for piRNA-mediated silencing at the single-cell level. We placed target sites...
  3. Letter: Population dynamics of PIWI-interacting RNAs (piRNAs) and their targets in Drosophila
    • Jian Lu and
    • Andrew G. Clark
    Genome Res. February 2010 20: 212-227; Published in Advance November 30, 2009, doi:10.1101/gr.095406.109
    ...; Nuzhdin 1999; Petrov et al. 2003; Gonzalez et al. 2008). Since themajority of piRNAswere generated fromTE loci, onewould expect that piRNAs would similarly experience rapid population dynamics. Previous studies have surveyed population dynamics of individual piRNA loci such as Su(Ste) (Lyckegaard...
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