Searching journal content for articles similar to Zhang et al. 17 (5): 612.

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  1. ...Chromosome inactivation (XCI) in females, but some Y-linked genes were retained during the course of sex chromosome evolution, and many X-linked genes did not become subject to XCI. We reconstructed gene-by-gene dosage sensitivities on the ancestral autosomes through phylogenetic analysis of microRNA (mi...
  2. ...Birth and expression evolution of mammalian microRNA genes Julien Meunier 1 , 2 , 7 , Frédéric Lemoine 1 , 4 , Magali Soumillon 1 , 2 , 5 , 6 , Angélica Liechti 1 , Manuela Weier 1 , Katerina Guschanski 1 , 2...
  3. ...considered to be a major contributor to adaptive evolutionary innovation. Here, I review the origin and evolution of new genes and their functions in eukaryotes, an area of research that has made rapid progress in the past decade thanks to the genomics revolution. Indeed, recent work has provided initial...
  4. ...conserved microRNA species display their signature tissue-specific expression patterns. In addition, we find a large rapidly evolving cluster of microRNAs on platypus chromosome X1, which is unique to monotremes. Platypus and echidna testes contain a robust Piwi-interacting (piRNA) system, which appears...
  5. ....Changes in gene expression were long thought to underlie the rapid evolution of phenotypic traits, including the evolution of human cognition. To date, a number of studies have investigated this topic and have reported scores of genes showing expression unique to the human brain in comparison to closely related...
  6. ...mitochondrial ( numt ) sequences, micro-RNAs, and evolutionary breakpoints that suggest historic balancing of translocation and inversion incidences in distinct mammalian lineages. Large numbers of single nucleotide polymorphisms (SNPs), deletion insertion polymorphisms (DIPs), and short tandem repeats (STRs...
  7. ...-scale duplication events thought to have occurred at the origin of vertebrates. We propose a model whereby gene duplication and the evolution of cis -regulatory elements can be considered in the context of increased morphological diversity and the emergence of the modern vertebrate body plan. Footnotes...
  8. ...Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes Alexander Stark 1 , 2 , 4 , 6 , Pouya Kheradpour 2 , 4 , Leopold Parts 2 , 5 , Julius Brennecke 3 , Emily Hodges 3 , Gregory J. Hannon 3...
  9. .../or have acquired lineage-specific functions. Indeed, many regulatory sequences and known functional noncoding RNAs, including many microRNAs, are not conserved over significant evolutionary distances, and recent evidence from the ENCODE project suggests that many functional elements show no detectable...
  10. ...clear that SINEs are frequently exapted by host s for use in important functional roles. A recent analysis indicates that as much as 20% of known human endogenous microRNAs are driven by Alu Pol III promoters ( Borchert et al. 2006 ). There are also accumulating examples of evolutionary conservation...
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