Searching journal content for articles similar to Zhang 9 (8): 681.

Displaying results 1-10 of 1248
For checked items
  1. ...analyses in cancer genomics.The ability of ScisTree2 to analyze a large number of cells may be useful in large-scale cancer genomics analyses. One such analysis is identifying rare cancer subclones, which can drive disease recurrence and therapy resistance. For example, relapse of acute myeloid leukemia...
  2. ...per sample, along with a computational tool for designing large-scale microsatellite panels. Our method addresses the greatest challenge for microsatellite profiling—“stutter” artifacts—with a low-temperature hybridization capture that significantly reduces these artifacts. We also developed...
  3. ...@eitech.edu.cnAbstractDeciphering the relationships between cis-regulatory elements (CREs) and target gene expression has been a long-standing unsolved problem in molecular biology, and the dynamics of CREs in different cell types make this problem more challenging. To address this challenge, we propose a scalable computational framework...
  4. ...technique that allows direct computation on encrypted data. We combine this approach with our efficient distributed computation techniques to minimize the overhead of cryptographic operations. Overall, our study provides the first practical demonstration of secure relative identification across large-scale...
  5. ...this gene could provide a viable therapeutic target in dogs (Urick and Bell 2020; Kawaguchi et al. 2021; Urick et al. 2021).Sequencing strategies for large-scale genomic analysesIn the past 10 years, there has been a steady decrease in the cost of short-read whole- sequencing (WGS) (Cullen and Friedenberg...
  6. ...: In this window In a new window Figure 2. Large scale-identification of species-specific orphan genes (SSOGs) in the human gut microbiome. (A) The main steps of the computational workflow of similarity searches. (B) Distribution of the SSOG proportion in a given species’ pan. The red dashed line denotes...
  7. ..., PCAoneArnoldi) alongside various other software packages widely used for large-scale PCA in genetics. These packages include FlashPCA2, PLINK2 (a faster reimplementation of FastPCA, Chang et al. 2015), TeraPCA and ProPCA. To assess the overall accuracy of all estimated PCs, we computed the mean explained...
  8. ...Large-scale detection and characterization of interchromosomal rearrangements in normozoospermic bulls using massive genotype and phenotype data sets Jeanlin Jourdain,1,2 Harmonie Barasc,3 Thomas Faraut,3 Anne Calgaro,3 Nathalie Bonnet,3 Camille Marcuzzo,4 Amandine Suin,4 Anne Barbat,2 Chris Hozé,1...
  9. ...Balancing Gene Ontology annotation specificity in protein function prediction 1 based on the protein sequence large graph 2 Jiangyi Shao1,2, Shutao Chen1, Ziwen Wang 1, Zixu Chen1,2, Bin Liu1,2* 3 1 School of Computer Science and Technology, Beijing Institute of Technology, 4 Beijing 100081, China...
    ACCEPTED MANUSCRIPT
  10. ...–specific, and changes during development in coordination with gene expression. Moreover, RT alterations are linked to abnormal gene expression, instability, and structural variation in multiple diseases, including cancer. However, mechanistic links between RT, large-scale 3D architecture, and transcriptional regulation...
For checked items

Preprint Server