Searching journal content for articles similar to Yun et al. 22 (6): 1089.

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  1. Research: Deep learning of the regulatory grammar of yeast 5′ untranslated regions from 500,000 random sequences
    • Josh T. Cuperus,
    • Benjamin Groves,
    • Anna Kuchina,
    • Alexander B. Rosenberg,
    • Nebojsa Jojic,
    • Stanley Fields,
    • and Georg Seelig
    Genome Res. December 2017 27: 2015-2024; Published in Advance November 2, 2017, doi:10.1101/gr.224964.117
    ...sequences. (E) The enrichment of 5′ UTRs based on the presence of an upstream AUG (uAUG) and a stop codon within the UTR. Upstream open reading frames (uORFs) are characterized by an in-frame uAUG followed by a termination codon before the primary ORF start codon, or an out-of-frame uAUG followed by a stop...
  2. Research: Roles for transcript leaders in translation and mRNA decay revealed by transcript leader sequencing
    • Joshua A. Arribere and
    • Wendy V. Gilbert
    Genome Res. June 2013 23: 977-987; Published in Advance April 11, 2013, doi:10.1101/gr.150342.112
    ...are known to have biological functions as translational regulators of gene expression (e.g., GCN4 [Mueller and Hinnebusch 1986] and CPA1 [Wang et al. 1999]). Consistent with potential regulatory importance, uAUG is the most conserved of all possible uNNN codons in the TL region (Fig. 5D). Taken together...
  3. Research: Noise–mean relationship in mutated promoters
    • Gil Hornung,
    • Raz Bar-Ziv,
    • Dalia Rosin,
    • Nobuhiko Tokuriki,
    • Dan S. Tawfik,
    • Moshe Oren,
    • and Naama Barkai
    Genome Res. December 2012 22: 2409-2417; Published in Advance July 20, 2012, doi:10.1101/gr.139378.112
    ...resolution reveals widespread regulatory roles for uAUGs. Genome Res 22: 1089–1097. Zenklusen D, Larson DR, Singer RH. 2008. Single-RNA counting reveals alternative modes of gene expression in yeast. Nat Struct Mol Biol 15: 1263–1271. Zhang Z, Qian W, Zhang J. 2009. Positive selection for elevated gene...
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  4. Research: Conserved non-AUG uORFs revealed by a novel regression analysis of ribosome profiling data
    • Pieter Spealman,
    • Armaghan W. Naik,
    • Gemma E. May,
    • Scott Kuersten,
    • Lindsay Freeberg,
    • Robert F. Murphy,
    • and Joel McManus
    Genome Res. February 2018 28: 214-222; Published in Advance December 18, 2017, doi:10.1101/gr.221507.117
    .... The evolving roles of alternative splicing. Curr Opin Struct Biol 14: 273–282. ↵Lee S, Liu B, Lee S, Huang SX, Shen B, Qian SB. 2012. Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution. Proc Natl Acad Sci 109: E2424–E2432. ↵Lynch M, Scofield DG, Hong X. 2005...
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