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Research: Genomic analysis of the causative agents of coccidiosis in domestic chickens
- Adam J. Reid,
- Damer P. Blake,
- Hifzur R. Ansari,
- Karen Billington,
- Hilary P. Browne,
- Josephine Bryant,
- Matt Dunn,
- Stacy S. Hung,
- Fumiya Kawahara,
- Diego Miranda-Saavedra,
- Tareq B. Malas,
- Tobias Mourier,
- Hardeep Naghra,
- Mridul Nair,
- Thomas D. Otto,
- Neil D. Rawlings,
- Pierre Rivailler,
- Alejandro Sanchez-Flores,
- Mandy Sanders,
- Chandra Subramaniam,
- Yea-Ling Tay,
- Yong Woo,
- Xikun Wu,
- Bart Barrell,
- Paul H. Dear,
- Christian Doerig,
- Arthur Gruber,
- Alasdair C. Ivens,
- John Parkinson,
- Marie-Adèle Rajandream,
- Martin W. Shirley,
- Kiew-Lian Wan,
- Matthew Berriman,
- Fiona M. Tomley,
- and Arnab Pain
Genome Res. October 2014 24: 1676-1685; Published in Advance July 11, 2014, doi:10.1101/gr.168955.113
...Eimeria , is one of the most important poultry diseases. Understanding the biology of Eimeria parasites underpins development of new drugs and vaccines needed to improve global food security. We have produced annotated genome sequences of all seven species of Eimeria that infect domestic chickens...
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RESEARCH: Gene Discovery by EST Sequencing in Toxoplasma gondiiReveals Sequences Restricted to the Apicomplexa
- James W. Ajioka,
- John C. Boothroyd,
- Brian P. Brunk,
- Adrian Hehl,
- Ledeana Hillier,
- Ian D. Manger,
- Marco Marra,
- G. Christian Overton,
- David S. Roos,
- Kiew-Lian Wan,
- Robert Waterston,
- and L. David Sibley
Genome Res. January 1, 1998 8: 18-28; doi:10.1101/gr.8.1.18
...-binding proteins. Proc. Natl. Acad. Sci. 92 : 7100 – 7104 . ↵ Reddy G.R. , Chakrabarti D. , Schuster S.M. , Ferl R.J. , Almira E.C. , Dame J.B. ( 1993 ) Gene sequence tags from Plasmodium falciparum genomic fragments prepared by the “genase” activity of mung bean nuclease. Proc. Natl. Acad. Sci. 90 : 9867 – 9871...
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Research: Genome-wide profiles of H3K9me3, H3K27me3 modifications, and DNA methylation during diapause of Asian corn borer (Ostrinia furnacalis)
- Pengfei Lv,
- Xingzhuo Yang,
- Xianguo Zhao,
- Zhangwu Zhao,
- and Juan Du
Genome Res. May 2024 34: 725-739; Published in Advance June 12, 2024, doi:10.1101/gr.278661.123
.... Diapause in larvae can be induced by manipulating photoperiod and temperature, as evidenced by studies conducted by Mutchmor and Mazurek (1959) and Guo et al. (2013). Neurons or metabolic organs that respond promptly to changes in photoperiod and temperature are located in the head, such as the circadian...
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Resource: Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii
- The Anopheles gambiae 1000 Genomes Consortium
Genome Res. October 2020 30: 1533-1546; Published in Advance September 28, 2020, doi:10.1101/gr.262790.120
..., making a valuable comparison. Among other eukaryotes, comparable data resources exist only for humans (The 1000 Genomes Project Consortium 2015) and malaria parasites (MalariaGEN Plasmodium falciparum Community Project 2019), and thus, there remains an absence of open genomic data for studying...
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Method: Genome-scale identification of cellular pathways required for cell surface recognition
- Sumana Sharma,
- S. Josefin Bartholdson,
- Amalie C.M. Couch,
- Kosuke Yusa,
- and Gavin J. Wright
Genome Res. September 2018 28: 1372-1382; Published in Advance June 18, 2018, doi:10.1101/gr.231183.117
...initiated by specific binding events made by plasma membrane–embedded receptors. These extracellular interactions are crucial for the normal development and function of multicellular organisms and can be exploited therapeutically because they are directly accessible to soluble drugs such as monoclonal...
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Resource: H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa
- Nicola J. Mulder,
- Ezekiel Adebiyi,
- Raouf Alami,
- Alia Benkahla,
- James Brandful,
- Seydou Doumbia,
- Dean Everett,
- Faisal M. Fadlelmola,
- Fatima Gaboun,
- Simani Gaseitsiwe,
- Hassan Ghazal,
- Scott Hazelhurst,
- Winston Hide,
- Azeddine Ibrahimi,
- Yasmina Jaufeerally Fakim,
- C. Victor Jongeneel,
- Fourie Joubert,
- Samar Kassim,
- Jonathan Kayondo,
- Judit Kumuthini,
- Sylvester Lyantagaye,
- Julie Makani,
- Ahmed Mansour Alzohairy,
- Daniel Masiga,
- Ahmed Moussa,
- Oyekanmi Nash,
- Odile Ouwe Missi Oukem-Boyer,
- Ellis Owusu-Dabo,
- Sumir Panji,
- Hugh Patterton,
- Fouzia Radouani,
- Khalid Sadki,
- Fouad Seghrouchni,
- Özlem Tastan Bishop,
- Nicki Tiffin,
- Nzovu Ulenga,
- and The H3ABioNet Consortium
Genome Res. February 2016 26: 271-277; Published in Advance December 1, 2015, doi:10.1101/gr.196295.115
...diversity in African populations presents a compelling opportunity for the delivery of more accurate diagnoses, new drugs, precision medicine, and a deeper understanding of susceptibility and resistance to infections and metabolic disease. In stark contrast to this opportunity, Africa's genomic analysis...
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