Searching journal content for articles similar to Yang et al. 14 (4): 517.

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  1. ..., predictions of the MH hypothesis can vary in opposite directions depending on the underlying pattern of indel mutations. In eukaryotes, where indel mutation patterns are typically biased toward insertions, reductions in population size are predicted to lead to increasing GS. Conversely, similar Ne reductions...
  2. ...that had previously been shown to have orthologous 1:1:1 relationships between mouse, rat, and human ( Rat Genome Sequencing Project Consortium 2004 ). We identified high-quality regions of alignments that included an insertion or deletion in either of the rodent sequences (see Methods). Only indel events...
  3. ...-specific estimates of substitution, and that utilize node-specific estimates of recombination will have substantially greater power to detect such patterns compared to simple human–mouse comparisons. Therefore, our rat–mouse–human comparative approach provides a beginning toward what will be a much more complete...
  4. ...Goldman, N A Smit Michael, O'Connor Simon S Yang T Furey KM Roskin Goldman, Nick 1549-5469 1088-9051 10.1101/gr.844103 genome;13/1/13 Covariation in Frequencies of Substitution, Deletion, Transposition, and Recombination During Eutherian Evolution Covariation in Frequencies of Substitution, Deletion...
  5. ...-to-female ratio of the number of germline cell divisions in rat and mouse. Thus, this is consistent with nucleotide substitutions and small indels occurring primarily during DNA replication. Footnotes Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.1971104. ↵ 6...
  6. ...double substitutions (e.g., AU 4 GC) and compatible single substitutions (e.g., AU4 GU). EvoFold, and related programs (Rivas and Eddy 2001; Washietl et al. 2005), detect this signal by analyzing the substitution pattern along genomic alignments and use it to identify these conserved RNA structures...
  7. ...element density, respectively. Second, we analyze sex chromosome versus autosome TE densities corrected for regional genomic effects. We discover that sex-chromosome bias in Alu and L1 distributions not only persists after accounting for these effects, but even presents differences in patterns...
  8. ..., Houston, Texas 77030, USA Abstract We have conducted a comprehensive search for conserved elements in vertebrate genomes, using genome-wide multiple alignments of five vertebrate species (human, mouse, rat, chicken, and Fugu rubripes ). Parallel searches have been performed with multiple...
  9. ...constitute independent sites. Using these data sets, we describe the patterns and rates of various microevolutionary features, such as point substitutions, insertions, and deletions, along all three branches of the unrooted tree that relates human, mouse, and rat. We furthermore estimate rates of evolution...
  10. .... Patterns of insertions and their covariation with substitutions in the rat, mouse and human s. Genome Res. (this issue). ↵ Yang, Z. 1994 . Estimating the pattern of nucleotide substitution. J. Mol. Evol. 39 : 105 -111. Yap, V.B. and Speed, T.P. 2004 . Modeling DNA base substitution in large genomic regions...
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