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  1. ...al. 2005 ; Reik 2007 ; Esteller 2008 ; Tiwari et al. 2008 ). However, recently, regions of methylated DNA have been correlated with the tissue-specific expression of several genes and with active coding regions across the ( Kumar and Biswas 1988 ; Ngo et al. 1996 ; Grunau et al. 2000 ; Imamura et al...
  2. ...epigenetic changes in the stromal cells of breast cancers. Nat. Genet. 37 : 899 – 905 . ↵ Imamura T. , Ohgane J. , Ito S. , Ogawa T. , Hattori N. , Tanaka S. , Shiota K. ( 2001 ) CpG island of rat sphingosine kinase-1 gene: Tissue-dependent DNA methylation status and multiple alternative first exons...
  3. ...and differentially methylated regions (TDMRs) in CpG islands in normal cells or tissues, and the methylation profile of the CpG islands is unique in each tissue or cell type ( Shiota et al. 2002 ). Information is still limited concerning DNA methylation in gene coding regions, although aberrant DNA methylation...
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