Searching journal content for articles similar to Xie et al. 20 (6): 804.

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  1. ...(Chuong et al. 2016), mammalian development (Chuong et al. 2013; Lynch et al. 2015; Nishihara et al. 2016), evolution of mammalian gene regulatory networks (Xie et al. 2010; Sundaram et al. 2014), or RNA interference in mice (Flemr et al. 2013). Our study represents a remarkable case of ERVL LTRs...
  2. ...et al. 2013; Sundaram et al. 2014; Ito et al. 2017; Pehrsson et al. 2019; Miao et al. 2020). TEs contribute to essential components of gene regulatory machinery in both humans and mice, including promoters, enhancers, and insulators. Specific TE subfamilies have rewired gene regulatory networks...
  3. ...-specific gene functions, suggesting that TEs are an important driving force for regulatory innovation. Taken together, our data suggest that TEs have significantly and continuously shaped gene regulatory networks during mammalian evolution. Footnotes [Supplemental material is available...
  4. ...of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA; 5Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, Pennsylvania 16802, USA Abstract Plasticity of gene regulatory encryption can permit DNA sequence divergence...
  5. ..., Guelph, ON N1G 2W1, Canada Corresponding author: michael.wilson@sickkids.caAbstractTransposable elements (TEs) provide a source of transcription factor (TF) binding sites that can rewire gene regulatory networks. NF-kB is an evolutionarily conserved TF complex primarily involved in innate immunity...
  6. ...paid to farmed fish - where relevant traits to aquaculture rely on early 15 developmental processes. This study reports a regulatory atlas of turbot 16 (Scophthalmus maximus) embryogenesis. 14,560 active genes were identified 17 in the embryonic transcriptome with > 90% showing differential expression...
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  7. ...RNA-mediated regulatory mechanisms and identify regulatory hubs and functional modules within the network.Here, via integrated molecular-functional analyses, we aimed to identify diapause-associated miRNAs and their larger role within the larger molecular rewiring during the cellular transition into dormancy...
  8. .... 2011; Negre et al. 2011; The ENCODE Project Consortium et al. 2012; Shen et al. 2012), their relevance to development and disease (Lindblad-Toh et al. 2011; The ENCODEProject Consortium et al. 2012), and the structure of the gene regulatory networks they implement (Suzuki et al. 2009; Marbach et al...
  9. ...evolution, TEs rewire host transcription networks through transposition and co-option, resulting in a wide variety of TE-derived regulatory elements, including promoters, enhancers, transcription terminators, and chromatin loop anchors (for reviews, see Feschotte and Gilbert 2012; Rebollo et al. 2012...
  10. ...motifs cooperatively modulate gene expression networks that are reused and rewired in the evolutionary acquisition of morphological diversity in metazoans. However, how these cis-regulatory elements diverge in sequence and in function and contribute to new gene regulatory networks and higher...
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