Searching journal content for articles similar to Wyman et al. 21 (9): 1450.

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  1. Resource: Small RNA expression and miRNA modification dynamics in human oocytes and early embryos
    • Pauliina Paloviita,
    • Christel Hydén-Granskog,
    • Dawit A. Yohannes,
    • Priit Paluoja,
    • Juha Kere,
    • Juha S. Tapanainen,
    • Kaarel Krjutškov,
    • Timo Tuuri,
    • Urmo Võsa,
    • and Sanna Vuoristo
    Genome Res. August 2021 31: 1474-1485; doi:10.1101/gr.268193.120
    ...to contribute to normal development.TENT2 presumably carries out the majority of miRNA A-tailing in early development (Neilsen et al. 2012) and is also expressed in human oocytes, zygotes, and embryos (Yan et al. 2013). However, the involvement of multiple cofactors and enzymes in the regulation of timing, rate...
  2. Resource: Dynamics of microRNA expression during mouse prenatal development
    • Sorena Rahmanian,
    • Rabi Murad,
    • Alessandra Breschi,
    • Weihua Zeng,
    • Mark Mackiewicz,
    • Brian Williams,
    • Carrie A. Davis,
    • Brian Roberts,
    • Sarah Meadows,
    • Dianna Moore,
    • Diane Trout,
    • Chris Zaleski,
    • Alex Dobin,
    • Lei-Hoon Sei,
    • Jorg Drenkow,
    • Alex Scavelli,
    • Thomas R. Gingeras,
    • Barbara J. Wold,
    • Richard M. Myers,
    • Roderic Guigó,
    • and Ali Mortazavi
    Genome Res. November 2019 29: 1900-1909; Published in Advance October 23, 2019, doi:10.1101/gr.248997.119
    ..., Cold Spring Harbor, New York 11724, USA ↵7 These authors contributed equally to this work. Corresponding author: ali.mortazavi@uci.eduAbstractMicroRNAs (miRNAs) play a critical role as posttranscriptional regulators of gene expression. The ENCODE Project profiled the expression of miRNAs...
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  3. Method: Systematic identification of edited microRNAs in the human brain
    • Shahar Alon,
    • Eyal Mor,
    • Francois Vigneault,
    • George M. Church,
    • Franco Locatelli,
    • Federica Galeano,
    • Angela Gallo,
    • Noam Shomron,
    • and Eli Eisenberg
    Genome Res. August 2012 22: 1533-1540; Published in Advance April 12, 2012, doi:10.1101/gr.131573.111
    ...RNAs are formed as part of the microRNA (miRNA) maturation process, and it is therefore expected that miRNAs are affected by A-to-I editing. Editing of miRNAs has the potential to add another layer of complexity to gene regulation pathways, especially if editing occurs within the miRNA–mRNA recognition site. Thus...
  4. Method: Degradation dynamics of microRNAs revealed by a novel pulse-chase approach
    • Matteo J. Marzi,
    • Francesco Ghini,
    • Benedetta Cerruti,
    • Stefano de Pretis,
    • Paola Bonetti,
    • Chiara Giacomelli,
    • Marcin M. Gorski,
    • Theresia Kress,
    • Mattia Pelizzola,
    • Heiko Muller,
    • Bruno Amati,
    • and Francesco Nicassio
    Genome Res. April 2016 26: 554-565; Published in Advance January 28, 2016, doi:10.1101/gr.198788.115
    ...–22 nt in length) that act in post-transcriptional regulation of gene expression in higher eukaryotes. Each miRNA can potentially target hundreds of genes, even simultaneously, causing their down-modulation through multiple mechanisms, including translational repression and/or mRNA destabilization...
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  5. Resource: Integrated annotations and analyses of small RNA–producing loci from 47 diverse plants
    • Alice Lunardon,
    • Nathan R. Johnson,
    • Emily Hagerott,
    • Tamia Phifer,
    • Seth Polydore,
    • Ceyda Coruh,
    • and Michael J. Axtell
    Genome Res. March 2020 30: 497-513; Published in Advance March 16, 2020, doi:10.1101/gr.256750.119
    ....eduAbstractPlant endogenous small RNAs (sRNAs) are important regulators of gene expression. There are two broad categories of plant sRNAs: microRNAs (miRNAs) and endogenous short interfering RNAs (siRNAs). MicroRNA loci are relatively well-annotated but compose only a small minority of the total sRNA pool; siRNA locus...
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