Searching journal content for articles similar to Wuchty 14 (7): 1310.

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  1. ...; Talbert et al. 2002; Allshire and Karpen 2008). In humans and yeast, the kinetochore consists of approximately 30 core subunits, within which CENP-A/Cse4 recruits the constitutive centromere-associated network (CCAN) (Yu et al. 2000; Yan et al. 2019; Pesenti et al. 2022; Yatskevich et al. 2022). CCAN...
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  2. ...expected under a neutral model of evolution. To obtain the background motif conservation rates, we adapted a method previously used in yeast (Doniger et al. 2005). Briefly, we take the sum of probabilities for all sequences that match a motif PWM, with each sequence probability calculated starting from...
  3. ...yeast Saccharomyces cerevisiae before human domestication remain poorly understood. Taiwan is regarded as part of this yeast's geographic birthplace, where the most divergent natural lineage was discovered. Here, we extensively sampled the broadleaf forests across this continental island to probe...
  4. ..., thus participating in protein structure diversity and evolution. We showed that amino acid sequences encoded by most yeast intergenic ORFs contain the elementary building blocks of protein structures. Moreover, they encompass the large structural state diversity of canonical proteins, with the majority...
  5. ...to nonmodel organisms lacking the extensive experimental data sets found in yeasts and mammals, and it can be done using sequence information alone for a relatively minuscule cost.ERC2.0 networks best predict organism-level cluster interactions in mammals compared to cellular processes in yeast...
  6. ...a multi–cell type extension of the weighted gene coexpression network analysis (WGCNA) framework, termed mWGCNA. Applying mWGCNA to RNA-seq data from six sorted immune cell populations (15 SLE, 10 healthy donors), we identify a coexpression module with interferon-stimulated genes (ISGs) among all cell...
  7. ...model on native 5′ UTRs. (A) Native 5′ UTR sequences were synthesized in 50-nt fragments and introduced into the HIS3-based selection system. (B) Correlation of a native library with the predictions from our convolutional neural network built from random sequences.In silico evolution of 5′ UTRs...
  8. ...). Evolution of virulence in Cryptococcus neoformans Genome Research 1209 www..org VNBII isolates are enriched for clinical isolation source relative to VNBI Although the VNB lineage was previously associated with a high frequency of environmental samples and the a mating type, we found differences between...
  9. ...Trichosporon yeasts as a model platform for interrogating early consequences of hybridization, but also highlight its multistage nature (Aury et al. 2006; Conant 2014), filling in a critical gap in the current understanding of eukaryotic evolution. Methods Genome sequencing and assembly T. coremiiforme JCM...
  10. ...(LDO) conjecture.” This study explores this conjecture, using a novel method to identify asymmetric evolution of paralogs and applying it to all gene families across the Tree of Life in the PANTHER database. Structural data for over 1 million proteins and expression data for 16 animals and 20 plants...
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