Searching journal content for articles similar to Wong and Choo 11 (4): 513.

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  1. Research: Polymorphic centromere locations in the pathogenic yeast Candida parapsilosis
    • Mihaela Ola,
    • Caoimhe E. O'Brien,
    • Aisling Y. Coughlan,
    • Qinxi Ma,
    • Paul D. Donovan,
    • Kenneth H. Wolfe,
    • and Geraldine Butler
    Genome Res. May 2020 30: 684-696; Published in Advance May 18, 2020, doi:10.1101/gr.257816.119
    ...features but are located within 30 kb of the old site. Centromeres can therefore move naturally from one chromosomal site to another, apparently spontaneously and in the absence of any significant changes in DNA sequence. Our observations are consistent with a model in which all centromeres are genetically...
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  2. Research: Centromere location in Arabidopsis is unaltered by extreme divergence in CENH3 protein sequence
    • Shamoni Maheshwari,
    • Takayoshi Ishii,
    • C. Titus Brown,
    • Andreas Houben,
    • and Luca Comai
    Genome Res. March 2017 27: 471-478; Published in Advance February 21, 2017, doi:10.1101/gr.214619.116
    ...; 3Department of Population Health and Reproduction, University of California, Davis, California 95616, USA Corresponding authors: smaheshwari@ucdavis.edu, lcomai@ucdavis.edu AbstractDuring cell division, spindle fibers attach to chromosomes at centromeres. The DNA sequence at regional centromeres...
  3. Research: Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles
    • Megan E. Aldrup-MacDonald,
    • Molly E. Kuo,
    • Lori L. Sullivan,
    • Kimberline Chew,
    • and Beth A. Sullivan
    Genome Res. October 2016 26: 1301-1311; Published in Advance August 10, 2016, doi:10.1101/gr.206706.116
    ...Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles Megan E. Aldrup-MacDonald 1 , 3 , Molly E. Kuo 1 , 3 , Lori L. Sullivan 1 , 3 , Kimberline Chew 1 and Beth A...
  4. Research: Efficient neocentromere formation is suppressed by gene conversion to maintain centromere function at native physical chromosomal loci in Candida albicans
    • Jitendra Thakur and
    • Kaustuv Sanyal
    Genome Res. April 2013 23: 638-652; Published in Advance February 25, 2013, doi:10.1101/gr.141614.112
    ...Efficient neocentromere formation is suppressed by gene conversion to maintain centromere function at native physical chromosomal loci in Candida albicans Jitendra Thakur and Kaustuv Sanyal 1 Molecular Mycology Laboratory, Molecular Biology and Genetics...
  5. Method: Automated annotation of human centromeres with HORmon
    • Olga Kunyavskaya,
    • Tatiana Dvorkina,
    • Andrey V. Bzikadze,
    • Ivan A. Alexandrov,
    • and Pavel A. Pevzner
    Genome Res. June 2022 32: 1137-1151; Published in Advance May 11, 2022, doi:10.1101/gr.276362.121
    ...). The development of an automated centromere annotation tool is a prerequisite for future centromere research that quickly moves to the stage when the complete s of hundreds of individuals will be assembled. These studies include population-wide analysis of human monomers and HORs, evolutionary studies...
  6. Method: OMKar automates genome karyotyping using optical maps to identify constitutional abnormalities
    • Siavash Raeisi Dehkordi,
    • Zhaoyang Jia,
    • Joey Estabrook,
    • Jen Hauenstein,
    • Neil Miller,
    • Naz Güleray-Lafci,
    • Jürgen Neesen,
    • Alex Hastie,
    • Alka Chaubey,
    • Andy Wing Chun Pang,
    • Paul Dremsek,
    • and Vineet Bafna
    Genome Res. December 2025 35: 2671-2681; Published in Advance November 14, 2025, doi:10.1101/gr.280536.125
    ..., aneuploidies, and other events that are directly relevant to constitutional disorders. In moving from cytogenetics to CMA and exome sequencing, much of that important information was lost. Current methods for SV calling typically do not capture the larger karyotype, making it harder to assign significance...
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  7. Perspective: The impact of long-read sequencing on human population-scale genomics
    • Tobias Rausch,
    • Tobias Marschall,
    • and Jan O. Korbel
    Genome Res. April 2025 35: 593-598; doi:10.1101/gr.280120.124
    ...in regions loaded with complex and tandemly oriented repeats, such as variable number tandem repeats (VNTRs), segmental duplications, telomeres, and centromeres (Ebert et al. 2021; Porubsky et al. 2022; Logsdon et al. 2024b). As such, long-read sequencing has begun to transform the investigation...
  8. LETTER: Recurrent Sites for New Centromere Seeding
    • Mario Ventura,
    • Stefania Weigl,
    • Lucia Carbone,
    • Maria Francesca Cardone,
    • Doriana Misceo,
    • Mariagrazia Teti,
    • Pietro D'Addabbo,
    • Annelise Wandall,
    • Erik Björck,
    • Pieter J. de Jong,
    • Xinwei She,
    • Evan E. Eichler,
    • Nicoletta Archidiacono,
    • and Mariano Rocchi
    Genome Res. September 2004 14: 1696-1703; doi:10.1101/gr.2608804
    .... Evolutionary centromere repositioning, a move of the centromere along the chromosome not accompanied by a pericentric inversion, is a phenomenon that we first described while studying primate evolution of chromosome 9. In some species, the centromere position exhibited an evolutionary history that appeared...
  9. Research: Long-read genome assembly of the insect model organism Tribolium castaneum reveals spread of satellite DNA in gene-rich regions by recurrent burst events
    • Marin Volarić,
    • Evelin Despot-Slade,
    • Damira Veseljak,
    • Brankica Mravinac,
    • and Nevenka Meštrović
    Genome Res. November 2024 34: 1878-1894; Published in Advance October 22, 2024, doi:10.1101/gr.279225.124
    ...into long arrays. Previous studies on many animal and plant species indicate preferential localization of satDNAs in the (peri)centromeric heterochromatin (Plohl et al. 2014). Heterochromatin represents a highly compact gene-poor specialized chromatin structure that is distinct from the gene...
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  10. Research: Evidence for selfing in a vertebrate from whole-genome sequencing
    • Astrid Böhne,
    • Zeynep Oğuzhan,
    • Ioannis Chrysostomakis,
    • Simon Vitt,
    • Denis Meuthen,
    • Sebastian Martin,
    • Sandra Kukowka,
    • and Timo Thünken
    Genome Res. December 2023 33: 2133-2142; Published in Advance December 7, 2023, doi:10.1101/gr.277368.122
    ...suppressed at the centromere (Talbert and Henikoff 2010; Sardell et al. 2018). If recombination events are more likely at telomeric regions (Haenel et al. 2018), alleles become randomly distributed among sister and nonsister chromatids at chromosomal peripheries. Resultantly, here maternal alleles...
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