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  1. ...genes. To infer horizontal gene transfer events between cyanobacteria and other phyla, we added homologs from 168 available s. We screened phylogenetic trees reconstructed for each of these extended gene families for highly supported monophyly of cyanobacteria (or lack of it). Cyanobacterial s reveal...
  2. ...conservation shows a much lower variance than the cooccurrence of genomes in COGs, which indicates that intragenome homogenization via recombination occurs in evolution much faster than intergenome homogenization via horizontal gene transfer and lineage-specific gene loss. The potential of using template...
  3. ...– 164 . ↵ Hennig W. ( 1965 ) Phylogenetic systematics. Ann. Rev. Entomol. 10 : 97 – 116 . ↵ Hilario E. , Gogarten J.P. ( 1993 ) Horizontal transfer of ATPase genes—the tree of life becomes a net of life. Biosystems 31 : 111 – 119 . ↵ Himmelreich R. , Hilbert H. , Plagens H. , Pirkl E. , Li B...
  4. ...or cellular features that have been analyzed. The canonical view, stemming mostly from ribosomal RNA (rRNA), elongation factors, and other molecules of the “informational” class, suggests that the ancestor was simple and prokaryotic-like ( Woese et al. 1990 ; Woese 1998 ) and that horizontal gene transfer...
  5. ....I. , Aravind L. , Grishin N.V. , Koonin E.V. ( 1999 ) Evolution of aminoacyl-tRNA synthetases—analysis of unique domain architectures and phylogenetic trees reveals a complex history of horizontal gene transfer events. Genome Res. 9 : 689 – 710 . ↵ Wootton J.C. , Federhen S. ( 1996 ) Analysis...
  6. ....F. 1999 . Phylogenetic classification and the universal tree. Science 284 : 2124 -2128. ↵ Doolittle, W.F. 2000 . The nature of the universal ancestor and the evolution of the proteome. Curr. Opin. Struct. Biol. 10 : 355 -358. ↵ Eisen, J.A. 2000 . Horizontal gene transfer among microbial s: New insights...
  7. ..., and identifies them as potentially fruitful targets for further experimentation. The universal COGs that are not three-domain primarily contain genes that encode proteins that are not integrated into specific large macromolecular complexes, for instance, the aminoacyl tRNA synthetases (14 of 28 COGs, reviewed...
  8. ...—Analysis of unique domain architectures and phylogenetic trees reveals a complex history of horizontal gene transfer events. Genome Res. 9 : 689 – 710 . ↵ Wolf Y.I. , Aravind L. , Koonin E.V. ( 1999b ) Rickettsiae and Chlamydiae: Evidence of horizontal gene transfer and gene exchange. Trends Genet. 15 : 173 – 175...
  9. ..., sequences of mevalonate pathway genes from these bacteria are deep branches on the phylogenetic trees (Fig. 3 and data not shown), and they do not cluster with the orthologs from animal s, which would seem an obvious source of horizontally transferred genes. This tree topology could, in principle...
  10. ...) Evolution of aminoacyl-tRNA synthetases — Analysis of unique domain architectures and phylogenetic trees reveals a complex history of horizontal gene transfer events. Genome Res. 9 : 689 – 710 . ↵ Wootton J.C. ( 1994 ) Non-globular domains in protein sequences: Automated segmentation using complexity...
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