Searching journal content for articles similar to Wilson et al. 15 (8): 1095.

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  1. ...P-element -induced lethal mutations that map to divisions 1–3, and determined the gene(s) whose function is likely to be affected by each insertion (Table 2 ). We have carried out a similar computational analysis on a collection of random EP-element insertions sequenced by the BDGP ( Rørth et al...
  2. ...in ES cells, but, unlike homologous recombination, it is a random approach that produces, with high throughput, a large number of insertional mutations across the mouse ( Durick et al. 1999 ; Stanford et al. 2001 ; Forrai and Robb 2005 ). Gene trapping disrupts genes by inserting an engineered DNA...
  3. ...(Hillenmeyer et al. 2008). Creating complete collections ofmutated genes inmulticellular organisms has been more challenging because effective methods to specifically and efficiently manipulate their s are lacking. Instead, investigators have relied on random mutagenesis followed by molecular screening...
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