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  1. .... The variables and indices are described in Supplemental Methods. (C) Distributional assumptions for the different variables in the SiCloneFit singlet model.A tumor population (clone) refers to a set of cells that share a common genotype as they descend from a common ancestor (Merlo et al. 2006). In the context...
  2. .... Non-Darwinian estimation: My ancestors, my genes’ ancestors. Genome Res. (this issue). doi: 10.1101/ gr.076539.108. Wu, C.-I, Shen, Y., and Tang, T. 2009. Evolution under canalization and the dual roles of microRNAs—A hypothesis. Genome Res. (this issue). doi: 10.1101/gr.084640.108. 692 Genome...
  3. ...6 million years, even while declining wide as part of the overall decline of mammalian isochores ( Belle et al. 2004 ). Perhaps the most intriguing aspect of a BCG force in evolution is that it acts like non-Darwinian selection. According to the theory of neutral evolution ( Takahata 1996 ), most...
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