Searching journal content for articles similar to Wei et al. 6 (8): 678.

Displaying results 1-10 of 6211

For checked items

view abstracts
download to citation manager

Select this article
Method: High-resolution genotype-free mapping of genetic variation with CRI-SPA-Map
- Sheila Lutz,
- Megan Lawler,
- Samuel Amidon,
- and Frank W Albert
Genome Res. March 23, 2026 gr.281514.125; Published in Advance March 23, 2026, doi:10.1101/gr.281514.125
...of the isolates 500 further increased mapping resolution. Sequencing efforts could be directed at isolates at an 501 association peak in genotype-free mapping. 502 The most frequent off-target effect of CRI-SPA-Map was rDNA recombination. While these 503 recombinants may simply be consequences of replication...
- Abstract
- Full Text (PDF)
OPEN ACCESS ARTICLEACCEPTED MANUSCRIPT
Select this article
Method: Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation
- Sophia N. Lee,
- Erin C. Banda,
- Lu Qiao,
- Sarah L. Thompson,
- Karan Singh,
- Ryan A. Hagenson,
- Teresa Davoli,
- Stefan F. Pinter,
- and Jason M. Sheltzer
Genome Res. March 2026 36: 547-560; Published in Advance January 12, 2026, doi:10.1101/gr.280425.125
...was extracted using the Qiagen RNeasy mini kit (Qiagen 74106). cDNA was synthesized using SuperScriptIV VILO master mix (Invitrogen 11756500). Quantitative PCR was performed for selected targets using PowerTrack SYBR green master mix (Applied Biosystems A46109) and quantified using the QuantStudio 6 flex real...
Select this article
Research: Cell-type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem cell–like cells
- Jennifer A. Urban,
- Daniel Ringwalt,
- John M. Urban,
- Wingel Xue,
- Ryan Gleason,
- Keji Zhao,
- and Xin Chen
Genome Res. January 2026 36: 83-101; Published in Advance December 10, 2025, doi:10.1101/gr.280809.125
...the GO analysis. (G) Differential transcript expression (log2 GSC/CySC) for select genes involved in DNA replication shows the higher expression of these genes in GSC-like cells (green bars). One gene, Cdc45, is differentially expressed in the CySC-like cells (magenta bar). (H) Confocal images of testis...
OPEN ACCESS ARTICLE
Select this article
Research: Nanopore direct RNA sequencing reveals METTL2A-mediated m³C sites in poly(A) RNA
- Shuhei Mitsutomi,
- Anzu Sugawara,
- Masahide Seki,
- Yutaka Suzuki,
- Sotaro Miyao,
- Haozhe Du,
- Kenji Takahashi,
- Yusuke Mizukami,
- Kenzui Taniue,
- and Nobuyoshi Akimitsu
Genome Res. November 2025 35: 2406-2417; Published in Advance October 30, 2025, doi:10.1101/gr.280269.124
...% FBS and 1 mM sodium pyruvate.Molecular cloningThe construct for expressing FLAG-tagged METTL2A (pcDNA3.1-FLAG-METTL2A) was generated by amplifying the open reading frame (ORF) of METTL2A from AsPC-1 cell cDNA using PrimeSTAR GXL DNA Polymerase (Takara, #R050A) and inserting it into the EcoRV and Xho...
Select this article
Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
- Andrew D. Bates,
- Dawid Grzela,
- Maciej Studzian,
- Louise Brennan,
- Moli Williams,
- Conor Fawcett,
- Beth Hammond,
- Manreen Grewal,
- Marcin Ratajewski,
- Lukasz Pulaski,
- and Urszula L. McClurg
Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
...were widely used to quantify transcript levels across the by hybridizing fluorescently labeled cDNA to thousands of predefined DNA probes immobilized on a solid surface. Each probe was designed to be complementary to a specific transcript, allowing its abundance in a sample to be inferred from...
OPEN ACCESS ARTICLE
Select this article
Research: Transcription and potential functions of a novel XIST isoform in male peripheral glia
- Kevin S. O'Leary,
- Meng-Yen Li,
- Kevyn Jackson,
- Lijie Shi,
- Elena Ezhkova,
- Bernice E. Morrow,
- and Deyou Zheng
Genome Res. February 2026 36: 257-274; Published in Advance December 12, 2025, doi:10.1101/gr.280832.125
...exhibit significant changes in XIST expression, but the direction of change depends on the disease (lower in PNP and higher in cardiomyopathy), suggesting that XIST (specifically sXIST because it is the only apparent transcript in male hearts) could potentially affect the expression of some genes...
OPEN ACCESS ARTICLE
Select this article
Research: Long-read DNA and cDNA sequencing identify cancer-predisposing deep intronic variation in tumor-suppressor genes
- Suleyman Gulsuner,
- Amal AbuRayyan,
- Jessica B. Mandell,
- Ming K. Lee,
- Greta V. Bernier,
- Barbara M. Norquist,
- Sarah B. Pierce,
- Mary-Claire King,
- and Tom Walsh
Genome Res. November 2024 34: 1825-1831; Published in Advance September 13, 2024, doi:10.1101/gr.279158.124
...large numbers of individuals become available, quantification of alternate splice events using tools such as LORALS for cDNA sequencing (Glinos et al. 2022) and NanoCount for direct RNA sequencing (Gleeson et al. 2022) will become more robust.Finally, the participants in this study are not typical...
Select this article
Resource: A map of enhancer regions in primary human neural progenitor cells using capture STARR-seq
- Sophia C. Gaynor-Gillett,
- Lijun Cheng,
- Manman Shi,
- Jason Liu,
- Gaoyuan Wang,
- Megan Spector,
- Qiuyu Guo,
- Le Qi,
- Mary Flaherty,
- Martha Wall,
- Ahyeon Hwang,
- Mengting Gu,
- Zhanlin Chen,
- Yuhang Chen,
- PsychENCODE Consortium,
- Jennifer R. Moran,
- Jing Zhang,
- Donghoon Lee,
- Mark Gerstein,
- Daniel Geschwind,
- and Kevin P. White
Genome Res. August 2025 35: 1887-1901; Published in Advance July 11, 2025, doi:10.1101/gr.279584.124
...of candidate selection. (C) The experimental workflow. Sheared genomic DNA was hybridized to probes specific for the candidate enhancer regions. These regions were then cloned into the STARR-seq plasmid and transfected into phNPCs. (D,E) The fold change correlation between the two technical replicates...
Select this article
Method: High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND
- Kehan Lang,
- Chenyang Jia,
- Siyu Li,
- Yi Guo,
- Dingjun Hu,
- and Shengquan Chen
Genome Res. March 26, 2026 ; Published in Advance March 26, 2026, doi:10.1101/gr.281350.125
...directions. Notably, the RNA-to-DNAm translation task under DNA purtubation demonstrated particularly robust performance, consistently achieving high clustering scores across all levels of simulated noise. This suggests that themodel effectively captures the regulatory signatures embedded in sc...
OPEN ACCESS ARTICLE
Select this article
Resource: A systems view on DNA damage response kinetics in Tetrahymena
- Emily Nischwitz,
- Vivien A.C. Schoonenberg,
- Rachel Mullner,
- Albert Fradera-Sola,
- Susanne Zimbelmann,
- Joshua J. Smith,
- and Falk Butter
Genome Res. January 28, 2026 ; Published in Advance January 28, 2026, doi:10.1101/gr.281000.125
...of both BER and NER (Fayyad et al. 2020; Kumar et al. 2022). Ionizing radiation (IR) induces direct DSBs, repaired by either HR or NHEJ (Chapman et al. 2012). Additionally, IR generates reactive oxygen species, repaired by BER and NER. Hydroxyurea (HU) indirectly impacts DNA through inhibition...

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Wei et al. 6 (8): 678.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: