Searching journal content for articles similar to Wang et al. 25 (6): 858.

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  1. ...splicing code models, we find evidence of splicing antagonism between CELF2 and the RBFOX family of splicing factors. We validate this functional antagonism through knockdown and overexpression experiments in human cells and find CELF2 represses RBFOX2 mRNA and protein levels. Because both families...
  2. ...an intricate series of RNA processing steps to achieve mRNA maturation. RNA editing and alternative splicing are two major RNA processing steps that can introduce significant modifications to the final gene products. By tackling these processes in isolation, recent studies have enabled substantial progress...
  3. ..., Germany; 7Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt, 60438 Frankfurt a.M., Germany ↵8 These authors contributed equally to this work. Corresponding authors: s.legewie@imb-mainz.de, j.koenig@imb-mainz.deAbstractAlternative splicing generates distinct mRNA isoforms...
  4. ...with members of the CUGBP1 and CUGBP2-like (CELF) family of splicing factors. The interaction of these different proteins is important for developmentally appropriate RNA splicing. MBNL proteins favor the adult splice isoforms and CUGBP1 favors the retention of fetal exons ( Ho et al. 2004 ). Consistent...
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