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Research: The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance
- Santosh S. Atanur,
- İnanç Birol,
- Victor Guryev,
- Martin Hirst,
- Oliver Hummel,
- Catherine Morrissey,
- Jacques Behmoaras,
- Xose M. Fernandez-Suarez,
- Michelle D. Johnson,
- William M. McLaren,
- Giannino Patone,
- Enrico Petretto,
- Charles Plessy,
- Kathleen S. Rockland,
- Charles Rockland,
- Kathrin Saar,
- Yongjun Zhao,
- Piero Carninci,
- Paul Flicek,
- Ted Kurtz,
- Edwin Cuppen,
- Michal Pravenec,
- Norbert Hubner,
- Steven J.M. Jones,
- Ewan Birney,
- and Timothy J. Aitman
Genome Res. June 2010 20: 791-803; Published in Advance April 29, 2010, doi:10.1101/gr.103499.109
...all genomic locations, providing a high likelihood at relatively low coverage that almost all allelic variation can be detected compared with other inbred strains. Here, we report the sequence of the spontaneously hypertensive rat using short-read next-generation sequence technology. We illustrate...
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Research: Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance
- Jingfeng Li,
- Keiko Akagi,
- Yongjun Hu,
- Anna L. Trivett,
- Christopher J.W. Hlynialuk,
- Deborah A. Swing,
- Natalia Volfovsky,
- Tamara C. Morgan,
- Yelena Golubeva,
- Robert M. Stephens,
- David E. Smith,
- and David E. Symer
Genome Res. May 2012 22: 870-884; Published in Advance February 23, 2012, doi:10.1101/gr.130740.111
....M A Trivett genome;gr.130740.111 10.1101/gr.130740.111 1088-9051 Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance Research Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance Jingfeng Li,1 Keiko Akagi,1 Yongjun Hu,2 Anna L...
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PERSPECTIVE: The opossum genome: Insights and opportunities from an alternative mammal
- Paul B. Samollow
Genome Res. August 2008 18: 1199-1215; doi:10.1101/gr.065326.107
...of mammalian s, especially for elucidating how variations in underlying genomic structural elements contribute to differences in gene regulation, expression, and function. In this light, the value of the opossum sequence for comparative analysis of structural evolution among vertebrate s is obvious...
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Research: LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans
- Shengjun Tan,
- Margarida Cardoso-Moreira,
- Wenwen Shi,
- Dan Zhang,
- Jiawei Huang,
- Yanan Mao,
- Hangxing Jia,
- Yaqiong Zhang,
- Chunyan Chen,
- Yi Shao,
- Liang Leng,
- Zhonghua Liu,
- Xun Huang,
- Manyuan Long,
- and Yong E. Zhang
Genome Res. December 2016 26: 1663-1675; Published in Advance October 20, 2016, doi:10.1101/gr.204925.116
...Harbor Laboratory Press; ISSN 1088-9051/16; www..org Genome Research 1663 www..org In principle, LTR retrotransposons could alsomediate the formation of retrocopies. Specifically, LTR retrotransposons have a close evolutionary relationship with retroviruses (Wicker et al. 2007), which replicate...
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Review: Contrasting genetic architectures in different mouse reference populations used for studying complex traits
- David A. Buchner and
- Joseph H. Nadeau
Genome Res. June 2015 25: 775-791; Published in Advance May 7, 2015, doi:10.1101/gr.187450.114
...and recombinant inbred strains. Each rectangle represents a chromosome, and each color represents the genetic contribution from a different mouse strain. Mitochondria are not shown. Buchner and Nadeau 778 Genome Research www..org with the CC and CSSs, but not the OS resources, detailed genotype information...
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REVIEW: Mammalian non-LTR retrotransposons: For better or worse, in sickness and in health
- Victoria P. Belancio,
- Dale J. Hedges,
- and Prescott Deininger
Genome Res. March 2008 18: 343-358; Published in Advance February 6, 2008, doi:10.1101/gr.5558208
...the activity of type I retrotransposons, which amplify in a “copy-and-paste” fashion through an RNA intermediate. For better or worse, the sequences of these retrotransposons are now wedded to the genomes of their mammalian hosts. Although there are several reported instances of the positive contribution...
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