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Research: Natural selection on cis and trans regulation in yeasts
- J.J. Emerson,
- Li-Ching Hsieh,
- Huang-Mo Sung,
- Tzi-Yuan Wang,
- Chih-Jen Huang,
- Henry Horng-Shing Lu,
- Mei-Yeh Jade Lu,
- Shu-Hsing Wu,
- and Wen-Hsiung Li
Genome Res. June 2010 20: 826-836; Published in Advance May 5, 2010, doi:10.1101/gr.101576.109
...found that expression level variation is usually numerically dominated by trans variants (Wang et al. 2007; Sung et al. 2009), even when single-input module genes were chosen to minimize the impact of trans variation (Wang et al. 2007). Additionally, in yeast only 52%–78%of expression...
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REVIEW: Unraveling transcription regulatory networks by protein–DNA and protein–protein interaction mapping
- Albertha J.M. Walhout
Genome Res. December 2006 16: 1445-1454; Published in Advance October 19, 2006, doi:10.1101/gr.5321506
..., it is important to identify all the cis -acting regulatory sequences and trans -acting factors involved, and how and when they interact to affect gene expression. Differential gene expression can be regulated at the transcriptional and at the post-transcriptional level by three types of trans -acting factors...

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