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Volik et al. 16 (3): 394
.
Displaying results 1-7 of
7
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Research
:
Assessment of palindromes as platforms for DNA amplification in breast cancer
Jamie Guenthoer
,
Scott J. Diede
,
Hisashi Tanaka
,
Xiaoyu Chai
,
Li Hsu
,
Stephen J. Tapscott
,
and
Peggy L. Porter
Genome Res.
February 2012
22
:
232
-
245
;
Published in Advance
July 13, 2011
,
doi:
10.1101/gr.117226.110
...–fusion–bridge (BFB) cycle. Therefore, palindromes might be associated with gene amplicons in
breast
cancer. To address this possibility, we coupled high-resolution palindrome profiling by the
Genome
-wide Analysis of Palindrome Formation (GAPF) assay with -wide copy-number analyses on a set of
breast
cancer cell...
Abstract
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Research
:
Transcriptional consequences of genomic structural aberrations in breast cancer
Koichiro Inaki
,
Axel M. Hillmer
,
Leena Ukil
,
Fei Yao
,
Xing Yi Woo
,
Leah A. Vardy
,
Kelson Folkvard Braaten Zawack
,
Charlie Wah Heng Lee
,
Pramila Nuwantha Ariyaratne
,
Yang Sun Chan
,
Kartiki Vasant Desai
,
Jonas Bergh
,
Per Hall
,
Thomas Choudary Putti
,
Wai Loon Ong
,
Atif Shahab
,
Valere Cacheux-Rataboul
,
Radha Krishna Murthy Karuturi
,
Wing-Kin Sung
,
Xiaoan Ruan
,
Guillaume Bourque
,
Yijun Ruan
,
and
Edison T. Liu
Genome Res.
May 2011
21
:
676
-
687
;
Published in Advance
April 5, 2011
,
doi:
10.1101/gr.113225.110
...no evidence for a transcript in current databases (see Supplemental Glossary).
Genome
Research 677 www..org Fusion genes in
breast
cancer had previously pioneered pair-end-tag sequencing of full-length cDNA from the MCF-7
transcriptome
(Ruan et al. 2007). This RNA paired-end-tag (RNA-PET) approach captures...
Abstract
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LETTER
:
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome
Oliver A. Hampton
,
Petra Den Hollander
,
Christopher A. Miller
,
David A. Delgado
,
Jian Li
,
Cristian Coarfa
,
Ronald A. Harris
,
Stephen Richards
,
Steven E. Scherer
,
Donna M. Muzny
,
Richard A. Gibbs
,
Adrian V. Lee
,
and
Aleksandar Milosavljevic
Genome Res.
February 2009
19
:
167
-
177
;
Published in Advance
December 3, 2008
,
doi:
10.1101/gr.080259.108
...A sequence-level map of chromosomal breakpoints in the MCF-7
breast
cancer cell line yields insights into the evolution of a cancer
genome
Oliver A. Hampton 1 , 3 , 5 , Petra Den Hollander 4 , 5 , Christopher A. Miller 1 , 3 , David A. Delgado 4...
Abstract
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Methods
:
Scanning the human genome at kilobase resolution
Jun Chen
,
Yeong C. Kim
,
Yong-Chul Jung
,
Zhenyu Xuan
,
Geoff Dworkin
,
Yanming Zhang
,
Michael Q. Zhang
,
and
San Ming Wang
Genome Res.
May 2008
18
:
751
-
762
;
Published in Advance
February 21, 2008
,
doi:
10.1101/gr.068304.107
...Scanning the human
genome
at kilobase resolution Jun Chen 1 , 6 , 7 , Yeong C. Kim 1 , 6 , Yong-Chul Jung 1 , Zhenyu Xuan 2 , Geoff Dworkin 3 , Yanming Zhang 4 , Michael Q. Zhang 2 , and San Ming Wang 1 , 5...
Abstract
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LETTER
:
Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs)
Yijun Ruan
,
Hong Sain Ooi
,
Siew Woh Choo
,
Kuo Ping Chiu
,
Xiao Dong Zhao
,
K.G. Srinivasan
,
Fei Yao
,
Chiou Yu Choo
,
Jun Liu
,
Pramila Ariyaratne
,
Wilson G.W. Bin
,
Vladimir A. Kuznetsov
,
Atif Shahab
,
Wing-Kin Sung
,
Guillaume Bourque
,
Nallasivam Palanisamy
,
and
Chia-Lin Wei
Genome Res.
June 2007
17
:
828
-
838
;
doi:
10.1101/gr.6018607
...either normal or unusual compositions. This unique nature of PET analysis makes it an ideal tool for uncovering unconventional features residing in the human
genome
. Using the PET approach for comprehensive
transcriptome
analysis, we were able to identify fusion transcripts derived from
genome
...
Abstract
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Research
:
Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes
Axel M. Hillmer
,
Fei Yao
,
Koichiro Inaki
,
Wah Heng Lee
,
Pramila N. Ariyaratne
,
Audrey S.M. Teo
,
Xing Yi Woo
,
Zhenshui Zhang
,
Hao Zhao
,
Leena Ukil
,
Jieqi P. Chen
,
Feng Zhu
,
Jimmy B.Y. So
,
Manuel Salto-Tellez
,
Wan Ting Poh
,
Kelson F.B. Zawack
,
Niranjan Nagarajan
,
Song Gao
,
Guoliang Li
,
Vikrant Kumar
,
Hui Ping J. Lim
,
Yee Yen Sia
,
Chee Seng Chan
,
See Ting Leong
,
Say Chuan Neo
,
Poh Sum D. Choi
,
Hervé Thoreau
,
Patrick B.O. Tan
,
Atif Shahab
,
Xiaoan Ruan
,
Jonas Bergh
,
Per Hall
,
Valère Cacheux-Rataboul
,
Chia-Lin Wei
,
Khay Guan Yeoh
,
Wing-Kin Sung
,
Guillaume Bourque
,
Edison T. Liu
,
and
Yijun Ruan
Genome Res.
May 2011
21
:
665
-
675
;
Published in Advance
April 5, 2011
,
doi:
10.1101/gr.113555.110
...using fragment sizes of 1, 10, and 20 Kb, and have found that 10 Kb is the optimal fragment size for SV analysis. Here, we report the characteristics of the
genomic
architectures of two epithelial cancers, i.e.,
breast
and gastric cancers. We comprehensively mapped SVs of eight
breast
cancer samples...
Abstract
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LETTER
:
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution
Graham R. Bignell
,
Thomas Santarius
,
Jessica C.M. Pole
,
Adam P. Butler
,
Janet Perry
,
Erin Pleasance
,
Chris Greenman
,
Andrew Menzies
,
Sheila Taylor
,
Sarah Edkins
,
Peter Campbell
,
Michael Quail
,
Bob Plumb
,
Lucy Matthews
,
Kirsten McLay
,
Paul A.W. Edwards
,
Jane Rogers
,
Richard Wooster
,
P. Andrew Futreal
,
and
Michael R. Stratton
Genome Res.
September 2007
17
:
1296
-
1303
;
Published in Advance
August 3, 2007
,
doi:
10.1101/gr.6522707
.... , et al. ( 2006 )
Decoding
the
fine-scale
structure of a
breast
cancer and
transcriptome
.
Genome
Res. 16 : 394 – 404 . Architectures of somatic
genomic
rearrangement in human cancer amplicons at sequence-level resolution Graham R. Bignell 1 , Thomas Santarius 1 , Jessica C.M. Pole 2 , Adam P. Butler 1...
Abstract
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