Searching journal content for articles similar to Villasante et al. 17 (12): 1909.

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  1. ...of TTAGGC-telomere isolatesBecause most of the nematode species that we analyzed had a canonical Nematoda TRM sequence, TTAGGC, the TTAGAC telomere probably evolved from its ancestral TTAGGC telomere via a single-nucleotide mutation of the telomerase RNA component gene. We hypothesized that subtelomeric...
  2. ...in that they are apparently synthesized, at least in part, by RNA polymerase rather than the conventional polyadenylation machinery. However, it is possible that the 3′ poly(A) residues might be added post-transcriptionally using conventional polyadenylation. There are a few non-LTR retrotransposons such as the Drosophila I...
  3. ...Drosophila. Leveraging 12 Drosophila s that span 40 Myr of evolution, Villasante, Abad, and colleagues detected at least one jockey-like, candidate telomeric retrotransposon in all 12 species (Villasante et al. 2007). These data implicated a single evolutionary event in a common ancestral sequence...
  4. ...lengthening in the absence of functional telomerase activity. ALT occurs in certain cancer cells in humans and in organisms in nature; for example, Drosophila uses retrotransposon rDNA sequences and onions use minisatellite rDNA sequences to maintain telomeres. This ALT process uses sequences other than...
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