Searching journal content for articles similar to Verhasselt and Volckaert 4 (2): 129.

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  1. ...or to genomic organization. To a large degree, this is a consequence of the limited number of high-quality chromosomal-level assemblies available until very recently. With advances in DNA sequencing technology, coupled with scaffolding using Hi-C, this limitation is being overcome (The Darwin Tree of Life...
  2. ...and assemble, and therefore, they are underrepresented or absent even in the best assemblies (for review, see Miga 2015; Lower et al. 2018). However, with the improvement of long-read sequencing technology, especially the Oxford Nanopore platform, it has recently been demonstrated that genomic loci made of satDNAs...
  3. ...colinearity through repair Genome Research 1233 www..org internal domain with many low-complexity motifs at the border of the captured fragment (Supplemental Fig. 1). We speculate that, whatever primary function these regions have for the transposon, theymay accidentally trigger the uptake of foreign DNA...
  4. ...Analyses of LTR-Retrotransposon Structures Reveal Recent and Rapid Genomic DNA Loss in Rice Jianxin Ma 1 , 2 , Katrien M. Devos 1 , 3 , and Jeffrey L. Bennetzen 1 , 2 , 4 1 Department of Biological Sciences, Purdue University, West...
  5. ...W. Diane Trout Schwarz ErichM Schwarz Steven G Kuntz J DeModena Wold, B Erich Sternberg, PW Kuntz Erich M Kuntz Steven G. De Buysscher, Tristan B Wold DeModena SG Kuntz Erich M Schwarz genome;gr.085472.108 10.1101/gr.085472.108 1088-9051 Multigenome DNA sequence conservation identifies Hox cis...
  6. ...). Complete sequencing of a single BAC revealed a patchwork of genomic DNA fragments ( Volik et al. 2003 ). Using this strategy, we have now conducted a detailed investigation of the structure at sequence-level resolution of somatic rearrangements in multiple amplified regions in cancer. We have shown...
  7. ...Ymin array. (C ) PFGE Southern hybridization of genomic DNAs probed with Ymin exhibits malespecific fragment lengths of predicted size (arrow) in five strains carrying a M.m. molossinus Y chromosome after digestion with enzymes BamHI (90.7 kb expected) and PacI (124 kb expected) (HindIII and XbaI data...
  8. ...and annotation Genomic DNA was sheared by sonication. The blunt-ends were created by mung bean nuclease, and 1.5-3.0 kb fragments were cloned into pUC18 digested with SmaI. The 8-10-kb inserts generated by Sau3AI/MboI were ligated into pUC18 digested with BamHI. Approximately 55,000 clones were sequenced from...
  9. ...are typically performed in two broad phases. In the initial “shotgun” phase, highly redundant sequence data are obtained by generating sequence reads from one or both insert ends of randomly selected subclones derived from the starting DNA (large-insert clone or whole ). This phase involves high...
  10. ...previous results from cDNA sequencing and long-distance PCR using human DNA as the template ( Uziel et al. 1996 ). It also proves the colinearity of the cosmid and genomic sequence. View larger version: In this window In a new window Figure 2. Schematic representation of the sequenced ATM locus. Boxes...
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