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Research: Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma
- Winnie S. Liang,
- William Hendricks,
- Jeffrey Kiefer,
- Jessica Schmidt,
- Shobana Sekar,
- John Carpten,
- David W. Craig,
- Jonathan Adkins,
- Lori Cuyugan,
- Zarko Manojlovic,
- Rebecca F. Halperin,
- Adrienne Helland,
- Sara Nasser,
- Christophe Legendre,
- Laurence H. Hurley,
- Karthigayini Sivaprakasam,
- Douglas B. Johnson,
- Holly Crandall,
- Klaus J. Busam,
- Victoria Zismann,
- Valerie Deluca,
- Jeeyun Lee,
- Aleksandar Sekulic,
- Charlotte E. Ariyan,
- Jeffrey Sosman,
- and Jeffrey Trent
Genome Res. April 2017 27: 524-532; doi:10.1101/gr.213348.116
...analysis of gene regulation at transcript resolution with RNA-seq. Nat Biotechnol 31: 46–53. Turajlic S, Furney SJ, Lambros MB, Mitsopoulos C, Kozarewa I, Geyer FC, Mackay A, Hakas J, Zvelebil M, Lord CJ, et al. 2012. Whole sequencing of matched primary and metastatic acral melanomas. Genome Res 22: 196...
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Research: Genome evolution during progression to breast cancer
- Daniel E. Newburger,
- Dorna Kashef-Haghighi,
- Ziming Weng,
- Raheleh Salari,
- Robert T. Sweeney,
- Alayne L. Brunner,
- Shirley X. Zhu,
- Xiangqian Guo,
- Sushama Varma,
- Megan L. Troxell,
- Robert B. West,
- Serafim Batzoglou,
- and Arend Sidow
Genome Res. July 2013 23: 1097-1108; Published in Advance April 8, 2013, doi:10.1101/gr.151670.112
...stages. To elucidate their role in cancer evolution we performed comparative whole-genome sequencing of early neoplasias, matched normal tissue, and carcinomas from six patients, for a total of 31 samples. By using somatic mutations as lineage markers we built trees that relate the tissue samples within...
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Commentary: An emerging toolkit for targeted cancer therapies
- Gordon B. Mills
Genome Res. February 2012 22: 177-182; doi:10.1101/gr.136044.111
..., Zvelebil M, Lord C Turajlic S, Furney SJ, Lambros MB, Mitsopoulos C, Kozarewa I, Geyer FC, MacKay A, Hakas J, Zvelebil M, Lord C, et al. 2012. Whole sequencing of matched primary and metastatic acral melanomas. Genome Res (this issue). doi: 10.1101/gr.125591.111. ↵ Vandin F, Upfal E, Raphael BJ Vandin F...

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