Searching journal content for articles similar to Torarinsson et al. 16 (7): 885.

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  1. ...is primarily driven by differences in unalignable regionsWe next investigated the sequence divergences underpinning the larger sizes of C. nigoni strains relative to C. briggsae strains. To this end, we leveraged the genomic variation detection tool SyRI (Goel et al. 2019), which systematically identifies...
  2. ...significantly bound SVAs, and 11 were rather found at DNA transposons. The remaining 71 KZFPs mapped to a mixture of low complexity or simple repeats, satellite DNAs and tRNAs. For 24, no particular class of genomic entity could be singled out perhaps due in part to difficulties in sequences alignment, notably...
  3. ...groups was reflected by the expression levels of the neighboring genes asmeasuredby RNA-seq (Fig. 1C). For example, genes next to S2-specific enhancers were specifically expressed in S2 cells but not in BG3 cells or OSCs, and the equivalent was true for BG3- or OSC-specific enhancers. Genes next...
  4. ...al. 2014), and cellular response to stress and stimulation (Shalek et al. 2014; Keren-Shaul et al. 2017; Golumbeanu et al. 2018). Gene expression levels in tens of thousands of single cells are now routinely measured in a single scRNA-seq experiment (Macosko et al. 2015), and more scRNA-seq data sets...
  5. ...functional role. We computationally screened vertebrate s for conserved RNA structures (CRSs), leveraging structure-based, rather than sequence-based, alignments. After careful correction for sequence identity and GC content, we predict ∼516,000 human genomic regions containing CRSs. We find...
  6. ...Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions Elfar Torarinsson 1 , 2 , Zizhen Yao 3 , Eric D. Wiklund 4 , Jesper B. Bramsen 4 , Claus Hansen 5 , Jørgen Kjems 4 , Niels Tommerup...
  7. ...genomic features that accurately discriminate between active and inactive TF binding events remain ambiguous. Recent studies have identified promoter-distal RNA polymerase II (RNAP2) binding at enhancer elements, suggesting that these interactions may serve as a marker for active regulatory sequences...
  8. ...Structured RNAs in the ENCODE selected regions of the human genome Stefan Washietl 1 , 14 , Jakob S. Pedersen 2 , Jan O. Korbel 3 , 4 , Claudia Stocsits 5 , Andreas R. Gruber 1 , Jörg Hackermüller 6 , Jana Hertel 5...
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  9. ...introns and in intergenic regions. We then developed a filtering pipeline to separate protein-coding transcripts from noncoding RNAs and identified a confident set of 6686 noncoding transcripts in 3859 genomic loci. Since the current reference genome, XenTro3, consists of hundreds of scaffolds instead...
  10. ...insertions and lineage-specific duplicated genes. Our findings suggest independent evolution of subterminal caps converging on a common genetic and epigenetic structure that promoted ectopic exchange as well as the emergence of novel genes at transition regions between euchromatin and heterochromatin...
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