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  1. ..., Bennetzen JL, Messing J. 2004b. On the tetraploid origin of the maize . Comp Funct Genomics 5: 281–284. Thomas BC, Pedersen B, Freeling M. 2006. Following tetraploidy in an Arabidopsis ancestor, genes were removed preferentially from one homeolog leaving clusters enriched in dose-sensitive genes. Genome Res...
  2. ...from the most recent paleotetraploidy ( Bowers et al. 2003 ; Thomas et al. 2006 ). Over 80% of the Arabidopsis can be homeologously paired using these α-pairs. Following this tetraploidy, most duplicate (homeologous) genes were fractionated from one or the other, but not both, homeologs, leaving ∼25...
  3. ...for the clustering of interacting genes such as coexpression or preservation of epistatic interactions. Here we conduct a novel test of a hypothesis that functionally linked genes in the same paralogon are preferentially retained in cis afterWGD.We compare the number of protein–protein interactions (PPIs) between...
  4. ...universal common ancestor of angiosperms. Comparative analysis of inferred homologous genes derived from this model shows patterns of preferential gene retention or loss after polyploidy and reveals large variability of nucleotide substitution rates among plant nuclear genomes. Footnotes ↵ 6...
  5. ...functioning in DNA repairGO overrepresentation tests were performed with the Arabidopsis orthologs of genes returned to single copy by the end of the root branch from each sub. Similar to previous findings (De Smet et al. 2013), we found that single-copy genes are enriched in biological processes such as DNA...
  6. ...the divergence of these two species, making it unlikely that the asymmetry reflects an allopolyploidy event. The small excess of asymmetrical gene loss observed here could have been caused by physical clustering of functional linked genes along chromosomes, as observed inhuman, yeast, and Arabidopsis (Makino...
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