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PERSPECTIVE: The canine genome
- Elaine A. Ostrander and
- Robert K. Wayne
Genome Res. December 2005 15: 1706-1716; doi:10.1101/gr.3736605
...as humans and the disease presentation and pathology of canine cancers is similar to analogous human tumors. Genetic studies are ongoing to find susceptibility genes for canine osteosarcoma, lymphoma, mast cell tumors, malignant histiocytosis, and kidney cancer, and a BAC CGH array resource...
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Letter: Copy number abnormalities in sporadic canine colorectal cancers
- Jie Tang,
- Shoshona Le,
- Liang Sun,
- Xiuzhen Yan,
- Mucheng Zhang,
- Jennifer MacLeod,
- Bruce LeRoy,
- Nicole Northrup,
- Angela Ellis,
- Timothy J. Yeatman,
- Yanchun Liang,
- Michael E. Zwick,
- and Shaying Zhao
Genome Res. March 2010 20: 341-350; Published in Advance January 19, 2010, doi:10.1101/gr.092726.109
...per canine tumor , with sizes ranging from 17 kb to 1.7 Mb with an average of 40–60 kb (varied with the tumors; see Fig. 3 for the identified CNAs for one tumor). These CNAs have a total probe number of between 5 and 208, with log2-ratio means ranging from 0.15 to 2.36. To validate our aCGH analyses...

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