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  1. ...following damage is particularly well studied in the yeast Candida albicans (Burrack and Berman 2012). Koren et al. (2010) suggested that, in this species, centromeres are associated with the presence of early origins of replication and that the formation of neocentromeres changes the activity of nearby...
  2. ...in most eukaryotes. DNA replication origins, origin binding proteins, and replication timing of centromere DNA are important determinants of centromere function. The epigenetically regulated regional centromeres in the budding yeast Candida albicans have unique DNA sequences that replicate earliest...
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