Searching journal content for articles similar to Tanay et al. 14 (5): 829.

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  1. ...selection acting to maintain similar expression levels in the face of new mutations, and has been seen not only in flies, but also in yeast (Tirosh et al. 2009), mice (Goncalves et al. 2012), and plants (Shi et al. 2012).Compensation for cis-regulatory divergence resulting from the fixation of trans...
  2. ...the sequences and factors involved, there has been no global examination of which features are critical to yeast gene identity, and therefore, the problem of how yeast (or any other eukaryote) delineates transcription units remains an open question. Many programs to identify genes in genomic DNA exist (e...
  3. ...analysis of the DNA-binding specificities of transcription factors with DNA microarrays. Nat Genet 36: 1331–1339. Mustonen V, Kinney J, Callan CG, La¨ssig M. 2008. Energy-dependent fitness: A quantitative model for the evolution of yeast transcription factor binding sites. Proc Natl Acad Sci 105: 12376...
  4. ...retention of WGD pairs while disfavoring the fixation of TD. Indeed, empirical data in yeast and Arabidopsis demonstrate that genes involved in signal transduction and transcription are more likely to be retained following a WGD but less likely to be retained in tandem (Seoighe and Gehring 2004; Davis...
  5. ...possible weak loci. To test if such selection exists, I used orthologous yeast promoters and developed a conservation score that compares the observed evolutionary changes in the total predicted promoter binding energy to those expected under a neutral model (Methods). The analysis therefore tested...
  6. ...for alignment coverage in coding regions, yielding 56% for the worm data set and 68% for the insects and yeasts. The degree of “smoothing” of the phylo-HMM was also constrained by forcing the expected amount of phylogenetic information (in an information theoretic sense) required to predict a conserved element...
  7. ...difference between trees at 18, and by the corresponding distance matrixes (the probability of incongruence is not rejected at P = 0.18 in the Mantel test). These results argue in favor of convergence in the pattern of global gene expression for Shigella /EIEC, a hallmark for adaptive evolution ( Harvey...
  8. ...; Tanay et al. 2004 ). Although a number of transcription factors and binding motifs have been studied in detail, some basic parameters of transcriptional regulation are not known. One important feature that has not been characterized is the amount of functional sequence under purifying selection in yeast...
  9. ...405 : 486 – 489 . ↵ Ihmels, J. , Bergmann, S. , Gerami-Nejad, M. , Yanai, I. , McClellan, M. , Berman, J. , Barkai, N. ( 2005 ) Rewiring of the yeast transcriptional network through the evolution of motif usage . Science 309 : 938 – 940 . ↵ Ivanova, N. , Dobrin, R. , Lu, R. , Kotenko, I. , Levorse, J...
  10. ...in yeast (using only duplicates) yielded contradictory results; one study argued that expression differences are not correlated with protein evolution ( Wagner 2000 ), whereas more recent work suggests a weak correlation ( Gu et al. 2002 ). However, a recent review ( Wolfe and Li 2003 ) concluded...
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