Searching journal content for articles similar to Takayama et al. 24 (5): 821.

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  1. Research: Combinatorial DNA methylation codes at repetitive elements
    • Christophe Papin,
    • Abdulkhaleg Ibrahim,
    • Stéphanie Le Gras,
    • Amandine Velt,
    • Isabelle Stoll,
    • Bernard Jost,
    • Hervé Menoni,
    • Christian Bronner,
    • Stefan Dimitrov,
    • and Ali Hamiche
    Genome Res. June 2017 27: 934-946; Published in Advance March 27, 2017, doi:10.1101/gr.213983.116
    ...(Mouse Genome Sequencing Consortium 2002). Previous data suggest that at least some of these repeat elements are methylated in ESCs (Shen et al. 2013) and undergo an extensive demethylation during plant development (Gehring et al. 2009). No comprehensive data are, however, available for the DNA -wide...
  2. Research: Deep sequencing of natural and experimental populations of Drosophila melanogaster reveals biases in the spectrum of new mutations
    • Zoe June Assaf,
    • Susanne Tilk,
    • Jane Park,
    • Mark L. Siegal,
    • and Dmitri A. Petrov
    Genome Res. December 2017 27: 1988-2000; Published in Advance October 27, 2017, doi:10.1101/gr.219956.116
    ...rates and patterns. Highlights of our results include: a high rate of multinucleotide mutation events at both short (∼5 bp) and long (∼1 kb) genomic distances, showing that mutation drives GC content lower in already GC-poor regions, and using our precise context-dependent mutation rates to predict long...
  3. Resource: Long-read assembly and comparative evidence-based reanalysis of Cryptosporidium genome sequences reveal expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions
    • Rodrigo P. Baptista,
    • Yiran Li,
    • Adam Sateriale,
    • Mandy J. Sanders,
    • Karen L. Brooks,
    • Alan Tracey,
    • Brendan R.E. Ansell,
    • Aaron R. Jex,
    • Garrett W. Cooper,
    • Ethan D. Smith,
    • Rui Xiao,
    • Jennifer E. Dumaine,
    • Peter Georgeson,
    • Bernard J. Pope,
    • Matthew Berriman,
    • Boris Striepen,
    • James A. Cotton,
    • and Jessica C. Kissinger
    Genome Res. January 2022 32: 203-213; Published in Advance November 11, 2021, doi:10.1101/gr.275325.121
    ...reveals a complete ortholog of the Dnmt2 methylase family. The C. parvum Dnmt2 sequence was previously annotated as truncated and lacking a DNMT-specific motif containing a prolyl-cysteinyl dipeptide (Abrahamsen et al. 2004; Ponts et al. 2013; Isaza et al. 2015). DNMT2 proteins share high sequence...
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  4. Research: Recruitment of histone modifications to assist mRNA dosage maintenance after degeneration of cytosine DNA methylation during animal evolution
    • Andrew Ying-Fei Chang and
    • Ben-Yang Liao
    Genome Res. September 2017 27: 1513-1524; Published in Advance July 18, 2017, doi:10.1101/gr.221739.117
    ...RNA dosage after duplication events that occurred in flies and worms does not involve DNA methylation To date, cytosineDNAmethylation has not been detected inC. elegans, and it is extremely rare in D. melanogaster (Simpson et al. 1986; Jeltsch 2010). Regarding the latter, the level of genomic cytosine...
  5. Research: Evolution and genomic signatures of spontaneous somatic mutation in Drosophila intestinal stem cells
    • Nick Riddiford,
    • Katarzyna Siudeja,
    • Marius van den Beek,
    • Benjamin Boumard,
    • and Allison J. Bardin
    Genome Res. August 2021 31: 1419-1432; Published in Advance June 24, 2021, doi:10.1101/gr.268441.120
    ...dynamics and mutational landscape operating within intestinal neoplasia over the short lifespan of the adult fly. Our findings provide unique insight into mutational dynamics operating over a short timescale in the genetic model system, Drosophila melanogaster.The accumulation of mutations in somatic...
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