Searching journal content for articles similar to Sutandy et al. 28 (5): 699.

Displaying results 1-10 of 5754

For checked items

view abstracts
download to citation manager

Select this article
Method: Simultaneous modeling of chromatin conformation changes from multiple single-cell interaction maps with ChromMovie
- Krzysztof H. Banecki,
- Haoxi Chai,
- Yijun Ruan,
- and Dariusz Plewczynski
Genome Res. April 8, 2026 ; Published in Advance April 8, 2026, doi:10.1101/gr.280985.125
...an important distinction. In contrast to averaged Hi-C modeling strategies, which rely heavily on distribution estimation and ensemble sampling, ChromMovie emphasizes the reconstruction of individual chromatin conformations. Figure 5. Benchmarking of ChromMovie computational time on a single NVIDIA A100 GPU...
OPEN ACCESS ARTICLE
Select this article
Research: RNA structure replaces the need for U2AF2 in splicing
- Chien-Ling Lin,
- Allison J. Taggart,
- Kian Huat Lim,
- Kamil J. Cygan,
- Luciana Ferraris,
- Robbert Creton,
- Yen-Tsung Huang,
- and William G. Fairbrother
Genome Res. January 2016 26: 12-23; Published in Advance November 13, 2015, doi:10.1101/gr.181008.114
...ofmodular structured introns enforce splice site selection in other species. Figure 5. The splicing of (AC)m-(GT)n introns requires components of U2 snRNP but not U2AF2. In vitro splicing substrates were prepared from the constructs used in Figure 4 and the model in vitro splicing construct Ad81...
Select this article
Method: The SeqSplice multiplexed minigene splicing assay for characterization and quantitation of variant-induced BRCA1 and BRCA2 splice isoforms
- Daffodil M. Canson,
- Michael T. Parsons,
- Gemma Moir-Meyer,
- Troy Dumenil,
- Gemma Montalban,
- Erica Lin,
- Terri P. McVeigh,
- Aimee L. Davidson,
- Shaun M. Bouckaert,
- Matt Trau,
- Darren Korbie,
- and Amanda B. Spurdle
Genome Res. September 2025 35: 2104-2115; Published in Advance August 6, 2025, doi:10.1101/gr.279557.124
...including targeted RT-PCR analysis and RNA sequencing-based tests (Casadei et al. 2019; Wai et al. 2020; Bournazos et al. 2022). Bioinformatic splicing predictions and RNA splicing assay data are then used as evidence in variant pathogenicity assessment models, including the widely adopted American College...
Select this article
Research: Meta-analysis of activated neurons reveals dynamic regulation of diverse classes of alternative splicing
- Keegan S. Krick,
- Marissa Maroni,
- Erica Korb,
- Kristen W. Lynch,
- and Elizabeth A. Heller
Genome Res. June 2025 35: 1301-1312; Published in Advance April 24, 2025, doi:10.1101/gr.280082.124
..., in regulating alternative splicing in the brain. However, the underlying molecular mechanisms through which chromatin regulates signal-induced alternative splicing remain elusive.Direct membrane depolarization of primary neurons using potassium chloride (KCl) serves as a widely used model of neuronal activity...
Select this article
Research: Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations
- Alicja Pacholewska,
- Matthias Lienhard,
- Mirko Brüggemann,
- Heike Hänel,
- Lorina Bilalli,
- Anja Königs,
- Felix Heß,
- Kerstin Becker,
- Karl Köhrer,
- Jesko Kaiser,
- Holger Gohlke,
- Norbert Gattermann,
- Michael Hallek,
- Carmen D. Herling,
- Julian König,
- Christina Grimm,
- Ralf Herwig,
- Kathi Zarnack,
- and Michal R. Schweiger
Genome Res. November 2024 34: 1832-1848; Published in Advance September 13, 2024, doi:10.1101/gr.279327.124
...CLIP. (F) Transcript regions of protein-coding genes targeted by the SF3B1 based on iCLIP. (G) Differential SF3B1 binding sites in K562-SF3B1K700E/wt versus K562-SF3B1wt/wt. (H) Metaprofiles of SF3B1 (top) and U2AF2 (bottom) binding centered at branch-point adenosine (left) and 3′ splice-site AG (right...
OPEN ACCESS ARTICLE
Select this article
Method: Automated chromatin profiling with spa-ChIP-seq uncovers the impacts of condition variations
- Yuwei Cao,
- Lauren Patel,
- Lauren Alcoser,
- Eric Mendenhall,
- Christopher Benner,
- Sven Heinz,
- and Alon Goren
Genome Res. January 2026 36: 129-141; Published in Advance December 12, 2025, doi:10.1101/gr.281320.125
Select this article
Research: Alternative splicing generates HER2 isoform diversity underlying antibody–drug conjugate resistance in breast cancer
- Gabriela D.A. Guardia,
- Carlos H. dos Anjos,
- Aline Rangel-Pozzo,
- Filipe F. dos Santos,
- Alexander Birbrair,
- Paula F. Asprino,
- Anamaria A. Camargo,
- and Pedro A.F. Galante
Genome Res. September 2025 35: 1942-1958; Published in Advance July 15, 2025, doi:10.1101/gr.280304.124
...tumors (Veiga et al. 2022). Second, we used computational models, classical and based on deep learning, to characterize the main features of the proteins encoded by these HER2 splicing isoforms, including their functional domains, structural elements, and cellular localization. Third, we analyzed...
Select this article
Method: Taurine pangenome uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle
- Sotiria Milia,
- Alexander S. Leonard,
- Xena Marie Mapel,
- Sandra Milena Bernal Ulloa,
- Cord Drögemüller,
- and Hubert Pausch
Genome Res. April 2025 35: 1041-1052; Published in Advance December 18, 2024, doi:10.1101/gr.279064.124
...Taurine pan uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle Sotiria Milia1,4, Alexander S. Leonard1,4, Xena Marie Mapel1, Sandra Milena Bernal Ulloa2, Cord Drögemüller3 and Hubert Pausch1 1Animal Genomics, ETH Zurich, Zurich 8092, Switzerland...
Select this article
Method: Infernape uncovers cell type–specific and spatially resolved alternative polyadenylation in the brain
- Bowei Kang,
- Yalan Yang,
- Kaining Hu,
- Xiangbin Ruan,
- Yi-Lin Liu,
- Pinky Lee,
- Jasper Lee,
- Jingshu Wang,
- and Xiaochang Zhang
Genome Res. October 2023 33: 1774-1787; Published in Advance October 31, 2023, doi:10.1101/gr.277864.123
...Infernape uncovers cell type–specific and spatially resolved alternative polyadenylation in the brain Bowei Kang1, Yalan Yang1, Kaining Hu1, Xiangbin Ruan1, Yi-Lin Liu2, Pinky Lee1, Jasper Lee1, Jingshu Wang2 and Xiaochang Zhang1,3 1Department of Human Genetics, The University of Chicago, Chicago...
OPEN ACCESS ARTICLE
Select this article
Method: Assessing conservation of alternative splicing with evolutionary splicing graphs
- Diego Javier Zea,
- Sofya Laskina,
- Alexis Baudin,
- Hugues Richard,
- and Elodie Laine
Genome Res. August 2021 31: 1462-1473; Published in Advance June 15, 2021, doi:10.1101/gr.274696.120
.... Here, we tackle the problem of describing the whole transcript variability observed in several species by generalizing the definition of splicing graph. We provide a practical solution to construct parsimonious evolutionary splicing graphs where each node is a minimal transcript building block defined...

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Sutandy et al. 28 (5): 699.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: