Searching journal content for articles similar to Sundaram et al. 24 (12): 1963.

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  1. ...(Schmidt et al. 2012; Wang et al. 2012). In mammals, TE-derived sequences contribute up to 40% of -wide binding sites for TFs located in TE-rich regions (Sundaram et al. 2014). It has been proposed that such co-option of TE-regulatory elements for gene regulatory networks can provide substantial...
  2. ...elements and can be used as promoters, enhancers, and insulators, providing fundamental building blocks for gene regulatory networks (Lamprecht et al. 2010; Babaian et al. 2016; Chuong et al. 2017; Sundaram and Wysocka 2020; Karttunen et al. 2023; Lawson et al. 2023; Shah et al. 2023; Liang et al. 2024...
  3. ..., Guelph, ON N1G 2W1, Canada Corresponding author: michael.wilson@sickkids.caAbstractTransposable elements (TEs) provide a source of transcription factor (TF) binding sites that can rewire gene regulatory networks. NF-kB is an evolutionarily conserved TF complex primarily involved in innate immunity...
  4. ..., Institute of Reproduction and Development, Fudan University, Shanghai 200437, China Corresponding authors: twang@wustl.edu, yue@northwestern.edu, hongboyang@fudan.edu.cnAbstractTransposable elements (TEs) encode regulatory elements that impact gene expression in multiple species, yet a comprehensive...
  5. ....The Cys2-His2 zinc finger (ZNF) is a short nucleic acid binding domain widespread in eukaryotes. ZNFs are often arranged in tandemly repeated arrays, resulting in proteins with versatile nucleic acid binding ability (Wolfe et al. 2000; Klug 2010; Najafabadi et al. 2017). In metazoans, tandem-repeat ZNF...
  6. ...active regulatory elements in the Atlantic salmon . 149 150 Immune stimulation remodels chromatin accessibility and histone modifications in 151 Atlantic salmon head kidney 152 Poly I:C stimulation led to widespread changes in chromatin accessibility, with an 153 approximately 25% increase in ATAC...
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  7. ...relocalization away from the endoplasmic reticulum, suggestive of novel TE dependent protein function in primate evolution. This work highlights the widespread dynamic nature of the spatiotemporal KZFP:TE transcriptome and its importance throughout TE mediated innovation and neurotypical human brain development...
  8. ...functional elements and strong enrichment for human genetic variants associated with blood cell phenotypes. The contribution of each epigenetic state in cCREs to gene regulation, inferred from a multivariate regression, was used to estimate epigenetic state regulatory potential (esRP) scores for each c...
  9. ...controlling wheat adaptation but also propose abundant indications of the widespread ongoing regulatory innovation and expansion introduced by lineage-specific TE insertion, degeneration, and domestication.MethodsPlant materials and growth conditionsTu seeds were surface-sterilized via a 10-min incubation...
  10. ...: 163-189. Smit A, Hubley R, Green P. 2015. RepeatMasker Open-4.0. 2013–2015. Sundaram V, Cheng Y, Ma Z, Li D, Xing X, Edge P, Snyder MP, Wang T. 2014. Widespread contribution of transposable elements to the innovation of gene regulatory networks. Genome research 24: 1963-1976. Sundaram V, Wang T. 2018...
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