Searching journal content for articles similar to Sun et al. 29 (3): 418.

Displaying results 1-5 of 5
For checked items
  1. Research: Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma
    • Huiwen Che,
    • Peiyong Jiang,
    • L.Y. Lois Choy,
    • Suk Hang Cheng,
    • Wenlei Peng,
    • Rebecca W.Y. Chan,
    • Jing Liu,
    • Qing Zhou,
    • W.K. Jacky Lam,
    • Stephanie C.Y. Yu,
    • So Ling Lau,
    • Tak Y. Leung,
    • John Wong,
    • Vincent Wai-Sun Wong,
    • Grace L.H. Wong,
    • Stephen L. Chan,
    • K.C. Allen Chan,
    • and Y.M. Dennis Lo
    Genome Res. February 2024 34: 189-200; Published in Advance February 26, 2024, doi:10.1101/gr.278556.123
    ...with a dominant peak ∼166 bp, with 10-bp periodicities below 150 bp, suggesting a nucleosomal origin (Lo et al. 2010; Ivanov et al. 2015). Thus, cfDNA is generally believed to be a population of short DNA molecules. Moreover, cfDNA fragments from different tissues may bear information tracing to their tissues...
    OPEN ACCESS ARTICLE
  2. Review: Artificial intelligence and machine learning in cell-free-DNA-based diagnostics
    • W.H. Adrian Tsui,
    • Spencer C. Ding,
    • Peiyong Jiang,
    • and Y.M. Dennis Lo
    Genome Res. January 2025 35: 1-19; doi:10.1101/gr.278413.123
    ...studies focus on circulating plasma DNA, unveiling a number of important biological features such as its tissues of origin and characteristic fragmentation patterns (Lo et al. 2021). Early interest in cfDNA was driven by the identification of circulating tumor DNA (ctDNA) in the plasma of cancer patients...
    OPEN ACCESS ARTICLE
  3. Research: Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA
    • Irena Hudecova,
    • Christopher G. Smith,
    • Robert Hänsel-Hertsch,
    • Chandra S. Chilamakuri,
    • James A. Morris,
    • Aadhitthya Vijayaraghavan,
    • Katrin Heider,
    • Dineika Chandrananda,
    • Wendy N. Cooper,
    • Davina Gale,
    • Javier Garcia-Corbacho,
    • Simon Pacey,
    • Richard D. Baird,
    • Nitzan Rosenfeld,
    • and Florent Mouliere
    Genome Res. February 2022 32: 215-227; Published in Advance December 20, 2021, doi:10.1101/gr.275691.121
    ...are released into the blood circulation following cell death and by active secretion (Stroun et al. 2000) while maintaining genetic and epigenetic signatures of the cell of origin (Heitzer et al. 2020). The fragmentation of cell-free DNA (cfDNA) in blood plasma can reflect its tissue of origin and mechanisms...
    OPEN ACCESS ARTICLE
  4. Research: Nuclease deficiencies alter plasma cell-free DNA methylation profiles
    • Diana S.C. Han,
    • Meng Ni,
    • Rebecca W.Y. Chan,
    • Danny K.L. Wong,
    • Linda T. Hiraki,
    • Stefano Volpi,
    • Peiyong Jiang,
    • Kathy O. Lui,
    • K.C. Allen Chan,
    • Rossa W.K. Chiu,
    • and Y.M. Dennis Lo
    Genome Res. November 2021 31: 2008-2021; Published in Advance September 1, 2021, doi:10.1101/gr.275426.121
    ...3-deficient mice had more hypomethylated fragments originating from increased fragmentation of open chromatin regions and CpG islands across the whole . The reduction of these fragments in cfDNA of DNASE1-deficient mice revealed the culprit to be DNASE1. The absence of DNASE1 activity in DNASE1...
    OPEN ACCESS ARTICLE
  5. Method: Detection and characterization of jagged ends of double-stranded DNA in plasma
    • Peiyong Jiang,
    • Tingting Xie,
    • Spencer C. Ding,
    • Ze Zhou,
    • Suk Hang Cheng,
    • Rebecca W.Y. Chan,
    • Wing-Shan Lee,
    • Wenlei Peng,
    • John Wong,
    • Vincent W.S. Wong,
    • Henry L.Y. Chan,
    • Stephen L. Chan,
    • Liona C.Y. Poon,
    • Tak Y. Leung,
    • K.C. Allen Chan,
    • Rossa W.K. Chiu,
    • and Y.M. Dennis Lo
    Genome Res. August 2020 30: 1144-1153; Published in Advance August 14, 2020, doi:10.1101/gr.261396.120
    ...the nascent field of fragmentomics of cell-free DNA (cfDNA) in plasma. The nonrandom fragmentation patterns of cfDNA, related to the tissues of origin, were first revealed by studying fetally and maternally derived cfDNA molecules in the plasma of pregnant women (Chan et al. 2004; Lo et al. 2010). The fetal...
    OPEN ACCESS ARTICLE
For checked items

Search Results

New Search

Modify Results

Citation format:
Results / page:
Results order:

This search

  • Alert me when new articles matching this search are published
  • Download all citations on this page to my citation manager

Preprint Server



Current Issue

  1. April 2026, 36 (4)
  1. Current Issue
  1. Alert me to new issues of Genome Research