Searching journal content for articles similar to Sun et al. 16 (2): 197.

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  1. Methods: Genome-wide discovery of human heart enhancers
    • Leelavati Narlikar,
    • Noboru J. Sakabe,
    • Alexander A. Blanski,
    • Fabio E. Arimura,
    • John M. Westlund,
    • Marcelo A. Nobrega,
    • and Ivan Ovcharenko
    Genome Res. March 2010 20: 381-392; Published in Advance January 14, 2010, doi:10.1101/gr.098657.109
    ...in mouse and zebrafish achieved a validation rate of 62%, significantly higher than what is expected by chance. These results support the existence of underlying cis -regulatory codes dictating tissue-specific transcription in mammalian genomes and validate our enhancer classifier strategy as a method...
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  2. Methods: Predicting tissue-specific enhancers in the human genome
    • Len A. Pennacchio,
    • Gabriela G. Loots,
    • Marcelo A. Nobrega,
    • and Ivan Ovcharenko
    Genome Res. February 2007 17: 201-211; Published in Advance January 8, 2007, doi:10.1101/gr.5972507
    ...of multicellular complexity; yet the genetic code of vertebrate gene regulation remains poorly understood. In an attempt to elucidate this code, we synergistically combined genome-wide gene-expression profiling, vertebrate genome comparisons, and transcription factor binding-site analysis to define sequence...
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  3. LETTER: Serum response factor binding sites differ in three human cell types
    • Sara J. Cooper,
    • Nathan D. Trinklein,
    • Loan Nguyen,
    • and Richard M. Myers
    Genome Res. February 2007 17: 136-144; Published in Advance January 2, 2007, doi:10.1101/gr.5875007
    ..., with a few additions from the microRNA registry, the Mammalian Gene Collection (MGC), and Ensembl ( Gerhard et al. 2004 ; Griffiths-Jones 2004 ; Birney et al. 2006 ). For each promoter, there is an average of 4 probes of 45–60 nucleotides each tiling ∼1000 bp upstream and 300 bp downstream. We hybridized...
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