Searching journal content for articles similar to Subramanian and Kumar 13 (5): 838.

Displaying results 1-10 of 44

For checked items

view abstracts
download to citation manager

Select this article
Research: Multiple Pristionchus pacificus genomes reveal distinct evolutionary dynamics between de novo candidates and duplicated genes
- Neel Prabh and
- Christian Rödelsperger
Genome Res. July 2022 32: 1315-1327; Published in Advance May 26, 2022, doi:10.1101/gr.276431.121
...to de novo genes, new duplicates might be engendered with a higher evolutionary stability at inception as their protein sequences are less likely to be toxic and they may readily interact with other proteins (Rödelsperger et al. 2019). This facilitates faster integration into cellular networks...
Select this article
Research: Positive selection in noncoding genomic regions of vocal learning birds is associated with genes implicated in vocal learning and speech functions in humans
- James A. Cahill,
- Joel Armstrong,
- Alden Deran,
- Carolyn J. Khoury,
- Benedict Paten,
- David Haussler,
- and Erich D. Jarvis
Genome Res. November 2021 31: 2035-2049; Published in Advance October 19, 2021, doi:10.1101/gr.275989.121
...), and obesity (Liu et al. 2014). In humans, positively selected accelerated regions (ARs), characterized by DNA sequence conservation in nonhuman species and faster than neutral DNA sequence evolution in humans, are enriched for neurological functions, potentially related to our evolution of larger brains...
OPEN ACCESS ARTICLE
Select this article
Research: Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes
- David Thybert,
- Maša Roller,
- Fábio C.P. Navarro,
- Ian Fiddes,
- Ian Streeter,
- Christine Feig,
- David Martin-Galvez,
- Mikhail Kolmogorov,
- Václav Janoušek,
- Wasiu Akanni,
- Bronwen Aken,
- Sarah Aldridge,
- Varshith Chakrapani,
- William Chow,
- Laura Clarke,
- Carla Cummins,
- Anthony Doran,
- Matthew Dunn,
- Leo Goodstadt,
- Kerstin Howe,
- Matthew Howell,
- Ambre-Aurore Josselin,
- Robert C. Karn,
- Christina M. Laukaitis,
- Lilue Jingtao,
- Fergal Martin,
- Matthieu Muffato,
- Stefanie Nachtweide,
- Michael A. Quail,
- Cristina Sisu,
- Mario Stanke,
- Klara Stefflova,
- Cock Van Oosterhout,
- Frederic Veyrunes,
- Ben Ward,
- Fengtang Yang,
- Golbahar Yazdanifar,
- Amonida Zadissa,
- David J. Adams,
- Alvis Brazma,
- Mark Gerstein,
- Benedict Paten,
- Son Pham,
- Thomas M. Keane,
- Duncan T. Odom,
- and Paul Flicek
Genome Res. April 2018 28: 448-459; Published in Advance March 21, 2018, doi:10.1101/gr.234096.117
....g., ancestral repeats). Thus, the entire genomic system—including coding, regulatory and neutral DNA—is evolutionarily coupled, implying that differences in mutation fixation rate should largely explain the observed acceleration in Muridae.Although the generation time of Muridae is much shorter than...
OPEN ACCESS ARTICLE
Select this article
Method: In silico phylogenomics using complete genomes: a case study on the evolution of hominoids
- Igor Rodrigues Costa,
- Francisco Prosdocimi,
- and W. Bryan Jennings
Genome Res. September 2016 26: 1257-1267; Published in Advance July 19, 2016, doi:10.1101/gr.203950.115
...neutral-coalescent methods of analysis. The reasons for this are twofold. First, because ALs are harvested from random genomic locations (Karl andAvise 1993), it is likely that theywill be composed of nonfunctional DNA (Meader et al. 2010; Lindblad-Toh et al. 2011; Ponting and Hardison 2011), which...
Select this article
Perspective: Human genomic disease variants: A neutral evolutionary explanation
- Joel T. Dudley,
- Yuseob Kim,
- Li Liu,
- Glenn J. Markov,
- Kristyn Gerold,
- Rong Chen,
- Atul J. Butte,
- and Sudhir Kumar
Genome Res. August 2012 22: 1383-1394; Published in Advance June 4, 2012, doi:10.1101/gr.133702.111
...that are consistent with the neutral theory of molecular evolution. (A) Proportions of single nucleotide variants (SNVs) with a rejected substitution (RS) score greater than 3 in coding and noncoding regions (Goode et al. 2010). A lower degree of genetic variation is permitted by purifying selection in functionally...
Select this article
Research: Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals
- Stefan Washietl,
- Manolis Kellis,
- and Manuel Garber
Genome Res. April 2014 24: 616-628; Published in Advance January 15, 2014, doi:10.1101/gr.165035.113
...elements, and more frequent single-exon transcripts. Remarkably, we find that ~20% of human lincRNAs are not expressed beyond chimpanzee and are undetectable even in rhesus. These hominid-specific lincRNAs are more tissue specific, enriched for testis, and faster evolving within the human lineage...
Select this article
Research: Comprehensive identification and analysis of human accelerated regulatory DNA
- Rachel M. Gittelman,
- Enna Hun,
- Ferhat Ay,
- Jennifer Madeoy,
- Len Pennacchio,
- William S. Noble,
- R. David Hawkins,
- and Joshua M. Akey
Genome Res. September 2015 25: 1245-1255; Published in Advance June 23, 2015, doi:10.1101/gr.192591.115
...(Supplemental Fig. 1a). Genomic landscape of human accelerated regulatory DNA We next investigated the set of haDHSs. Overall, these elements have evolved at approximately four times the neutral rate in the human lineage, while other primate branches have evolved at less than half of the neutral rate (Fig. 3A...
Select this article
LETTER: Biased clustered substitutions in the human genome: The footprints of male-driven biased gene conversion
- Timothy R. Dreszer,
- Gregory D. Wall,
- David Haussler,
- and Katherine S. Pollard
Genome Res. October 2007 17: 1420-1430; Published in Advance September 4, 2007, doi:10.1101/gr.6395807
...change is fueled by neutral stochastic forces acting upon random mutations, and the remainder is due to adaptive selection. As described by Nagylaki (1983) , gene conversion is a neutral evolutionary force that can lead to increased genetic drift and faster evolution, mimicking directional selection...
OPEN ACCESS ARTICLE
Select this article
Research: Contrasting GC-content dynamics across 33 mammalian genomes: Relationship with life-history traits and chromosome sizes
- Jonathan Romiguier,
- Vincent Ranwez,
- Emmanuel J.P. Douzery,
- and Nicolas Galtier
Genome Res. August 2010 20: 1001-1009; Published in Advance June 7, 2010, doi:10.1101/gr.104372.109
...D,Gautier C, Bernardi G. 1988. The compositional distribution of coding sequences and DNA molecules in humans and murids. J Mol Evol 27: 311–320. Nikolaev SI, Montoya-Burgos JI, Popadin K, Parand L, Margulies EH. 2007. Life-history traits drive the evolutionary rates of mammalian coding and noncoding genomic...
Select this article
LETTER: Dispensability of mammalian DNA
- Cory McLean and
- Gill Bejerano
Genome Res. November 2008 18: 1743-1751; Published in Advance October 2, 2008, doi:10.1101/gr.080184.108
...that ultraconserved-like elements are over 300-fold less likely than neutral DNA to have been lost during rodent evolution. In fact, many thousands of noncoding loci under purifying selection display near uniform indispensability during mammalian evolution, largely irrespective of nucleotide conservation level...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Subramanian and Kumar 13 (5): 838.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: