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  1. ...-resolution bacterial contig map. The contigs will be sequenced by the chromosome 21 sequencing project within the framework of the German Human Genome Programme. RESULTS Construction of a PAC-Pocket Sublibrary Enriched for the Region A YAC contig from the integrated cosmid-pocket map published previously ( Nizetic et...
  2. ...fingerprints and by PAC-to-PAC hybridizations on Southern blots. The final contig contains 156 clones, providing an average 7 × coverage across 2.8 Mb, that is, each marker hit 7 PACs on average. In all, 91 markers were mapped on the 2.8 Mb contig (1/31 kb). Thirty-four of these are genes or ESTs and 40...
  3. ...electroforesis. J. Mol. Biol. 98 : 503 – 517 . ↵ Stone N.E. , Fan J.-B. , Willour V. , Pennacchio L.A. , Warrington J.A. , Hu A. , de la Chapelle A. , Lehesjoki A.-E. , Cox D.R. , Myers R.M. ( 1996 ) Construction of a 750-kb bacterial clone contig and restriction map in the region of human chromosome 21...
  4. ...fragments as large as 100 kilobases pairs. Proc. Natl. Acad. Sci. 87 : 103 – 107 . ↵ Stone N.E. , Fan J.B. , Willour V. , Pennacchio L.A. , Warrington J.A. , de la Chapelle A. , et al. ( 1996 ) Construction of a 750-kb bacterial clone contig and restriction map in the region of human chromosome 21...
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