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  1. ...European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, D-69117 Heidelberg, Germany; 3Collaboration for Joint PhD Degree between EMBL and Heidelberg University, Faculty of Biosciences, D-69117 Heidelberg, Germany; 4Aix Marseille Univ, INSERM, TAGC, 13009 Marseille, France...
  2. ...Department of Soil and Crop Science, Colorado State University, Fort Collins, Colorado 80523, USA; 5United States Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA; 6Donald Danforth Plant Science Center, St. Louis, Missouri 63132, USA...
  3. ..., and genome-wide analyses of quantitative traits identify novel candidate genes. The DGRP lines, sequence data, genotypes, quality scores, phenotypes, and analysis and visualization tools are publicly available. Footnotes ↵ 10 Joint first authors ↵ 11 Senior authors ↵ 16...
  4. ...the construction of a more comprehensive, accurate SV map (Cridland and Thornton 2010). The DGRP project has recently generated deep-sequence coverage (median coverage = 183) data for a panel of isogenic fly lines. These lines were inbred over 20 generations, yielding a set of isogenic strains distributed across...
  5. ...of the total segregating variation. As a genetic reference panel freely available to the community (FlyRILs.org) the DSPR allows multiple traits to be assayed Fine mapping QTL in the DSPR Genome Research 1563 www..org in multiple environments, facilitating analyses of pleiotropy, genotype...
  6. ..., we ran smoove call on each individual sample, then smoove merge to combine all sets of calls from each individual into a merged call set followed by smoove genotype to perform joint genotyping of each sample over the merged call set, and, finally, smoove paste to concatenate the results into a single...
  7. ...the joint posterior distribution of all unknowns, including the main and epistatic effects, given the observed data (Yi et al. 2007). Using this approach, Yi and colleagues detected Figure 1. Effect sizes (expressed as odds ratios) in human -wide association studies. Data are from http...
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