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Research: Identical bacterial populations colonize premature infant gut, skin, and oral microbiomes and exhibit different in situ growth rates
- Matthew R. Olm,
- Christopher T. Brown,
- Brandon Brooks,
- Brian Firek,
- Robyn Baker,
- David Burstein,
- Karina Soenjoyo,
- Brian C. Thomas,
- Michael Morowitz,
- and Jillian F. Banfield
Genome Res. April 2017 27: 601-612; Published in Advance January 10, 2017, doi:10.1101/gr.213256.116
...to single nucleotide polymorphisms, given that CRISPR spacers that otherwise distinguish the variants did not have targets in the same samples. The lack of coexisting CRISPR spacer targets (yet presence of targets in other samples) is likely due to the phage immunity conferred by the CRISPR spacers...
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Method: Genome of the pathogen Porphyromonas gingivalis recovered from a biofilm in a hospital sink using a high-throughput single-cell genomics platform
- Jeffrey S. McLean,
- Mary-Jane Lombardo,
- Michael G. Ziegler,
- Mark Novotny,
- Joyclyn Yee-Greenbaum,
- Jonathan H. Badger,
- Glenn Tesler,
- Sergey Nurk,
- Valery Lesin,
- Daniel Brami,
- Adam P. Hall,
- Anna Edlund,
- Lisa Z. Allen,
- Scott Durkin,
- Sharon Reed,
- Francesca Torriani,
- Kenneth H. Nealson,
- Pavel A. Pevzner,
- Robert Friedman,
- J. Craig Venter,
- and Roger S. Lasken
Genome Res. May 2013 23: 867-877; Published in Advance April 5, 2013, doi:10.1101/gr.150433.112
...species can be observed in clustered regularly interspaced short palindromic repeats (CRISPR) sequences, which are noncontinuous direct repeats separated by variable (spacer) sequences that have been shown to confer immunity to phage ( Jansen et al. 2002; Barrangou et al. 2007). Amplification and de novo...
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March 2026, 36 (3)

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