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Resource: Zebrafish transposable elements show extensive diversification in age, genomic distribution, and developmental expression
- Ni-Chen Chang,
- Quirze Rovira,
- Jonathan Wells,
- Cédric Feschotte,
- and Juan M. Vaquerizas
Genome Res. July 2022 32: 1408-1423; Published in Advance January 5, 2022, doi:10.1101/gr.275655.121
...been shown to be the source of new protein coding exons, RNA-binding motifs, and microRNA target sites (Lev-Maor et al. 2003; Zarnack et al. 2013; Petri et al. 2019; Cosby et al. 2021). Our analyses reveal that DNA transposon transcription is more often gene-dependent than retroelement transcription...
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Research: Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution
- Justyna A. Resztak,
- Julong Wei,
- Samuele Zilioli,
- Edward Sendler,
- Adnan Alazizi,
- Henriette E. Mair-Meijers,
- Peijun Wu,
- Xiaoquan Wen,
- Richard B. Slatcher,
- Xiang Zhou,
- Francesca Luca,
- and Roger Pique-Regi
Genome Res. June 2023 33: 839-856; Published in Advance July 13, 2023, doi:10.1101/gr.276765.122
...to prevent severe complications from coronavirus disease 2019 (COVID-19) (Horby et al. 2021). Severe COVID-19 is thought to be a consequence of an exaggerated response of the immune system to SARS-CoV-2 infection (Anka et al. 2021). Elevated production of proinflammatory cytokines results in tissue damage...
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