Searching journal content for articles similar to Sharov et al. 15 (5): 748.

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  1. ...length as a function of the location of the midpoint of each fragment and colored the points based on their local density. The result is a near-nucleotide-resolution -wide view of chromatin occupancy for each deletion strain (Fig. 1D–F).View larger version: In this window In a new window Figure 1. Genome-wide...
  2. ...-in orientations in vitro (Song et al. 2011, 2014). However, to what extent nucleosomes modulate CPD deamination in other sequence contexts and across the of intact cells remains unclear.Genome-wide sequencing methods have emerged as powerful tools to understand how different genomic and chromatin contexts impact...
  3. .... Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules. Genome Res 22: 2497–2506. doi:10.1101/gr.143008.112 ↵Kouzine F, Gupta A, Baranello L, Wojtowicz D, Ben-Aissa K, Liu J, Przytycka TM, Levens D. 2013. Transcription-dependent dynamic supercoiling is a short...
  4. ...classifier for -wide detection. The limitation of the supervised classification framework primarily manifests in its detection speed and relatively small reception fields. Genome-wide detection with a binary classifier can be computationally inefficient as the small window causes scanning to be resource...
  5. ...window Figure 2. Genome-wide diversity and differentiation for common voles, M. arvalis, from the Orkney archipelago (brown) versus continental individuals (green). Density distributions (top) and Manhattan plots (bottom) for π, Tajima's D, and FST in 50 kb windows along the . Different chromosomes...
  6. ...@iisermohali.ac.inAbstractIsoform diversity is known to enhance a gene's functional repertoire by producing protein variants with distinct functional implications. Despite numerous studies on transcriptome diversifying processes (alternative splicing/transcription), understanding their extent and correlated impact on proteome diversity...
  7. ...map spl-TRs in a -wide manner across tissues throughout the whole body by using the Genotype-Tissue expression (GTEx) v8 data set, a population-scale resource of whole- sequencing (WGS) and RNA sequencing (RNA-seq).ResultsGenome-wide identification of spl-TRs across 49 tissuesWe discovered cis spl...
  8. ...populations (O'Dushlaine and Shields 2008; McIver et al. 2011; Willems et al. 2014; Mallick et al. 2016), representing an important source of human genetic variation that, in some cases, has been implicated in human disease (Hannan 2018). Multiple studies have shown transcriptional and epigenetic effects...
  9. ...factor binding sites which can potentially contribute to regulation of nearby genes (Shimosuga et al. 2017), and has been shown to induce alternative splicing of nearby exons (Wang et al. 2019). Finally, this IAP element also forms an exon of a noncanonical transcript of Msh3, although it remains unclear...
  10. ...://creativecommons.org/licenses/by-nc/4.0/.References ↵Arnold CD, Gerlach D, Stelzer C, Boryń ŁM, Rath M, Stark A. 2013. Genome-wide quantitative enhancer activity maps identified by STARR-seq. Science 339: 1074–1077. doi:10.1126/science.1232542 ↵Assaf ZJ, Tilk S, Park J, Siegal ML, Petrov DA. 2017. Deep sequencing of natural...
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