Searching journal content for articles similar to Sen et al. 25 (8): 1196.

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  1. Research: Trans-splicing enhances translational efficiency in C. elegans
    • Yu-Fei Yang,
    • Xiaoqing Zhang,
    • Xuehua Ma,
    • Taolan Zhao,
    • Qiushi Sun,
    • Qing Huan,
    • Shaohuan Wu,
    • Zhuo Du,
    • and Wenfeng Qian
    Genome Res. September 2017 27: 1525-1535; Published in Advance July 6, 2017, doi:10.1101/gr.202150.115
    ...that SL1 trans-splicing likely enhances translational efficiency by shortening the native 5′ UTRs, hence reducing the presence of upstream start codons (uAUG) and weakening mRNA secondary structures. Taken together, our study elucidates the global function of trans-splicing in enhancing translational...
  2. Research: A novel translational control mechanism involving RNA structures within coding sequences
    • Jennifer Jungfleisch,
    • Danny D. Nedialkova,
    • Ivan Dotu,
    • Katherine E. Sloan,
    • Neus Martinez-Bosch,
    • Lukas Brüning,
    • Emanuele Raineri,
    • Pilar Navarro,
    • Markus T. Bohnsack,
    • Sebastian A. Leidel,
    • and Juana Díez
    Genome Res. January 2017 27: 95-106; Published in Advance November 7, 2016, doi:10.1101/gr.209015.116
    ...this conclusion, immunoprecipitation analyses showed that Dhh1 binds to the translation initiation factors eIF4E, eIF4A, and eIF4G in an RNase-resistant manner (Fig. 2E). A stem–loop within the CDS of RNA2 confers dependence on Dhh1 for translation To identify which BMV RNA2 regions conferDhh1-dependence...
  3. Research: nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
    • Valentina Gandin,
    • Laia Masvidal,
    • Laura Hulea,
    • Simon-Pierre Gravel,
    • Marie Cargnello,
    • Shannon McLaughlan,
    • Yutian Cai,
    • Preetika Balanathan,
    • Masahiro Morita,
    • Arjuna Rajakumar,
    • Luc Furic,
    • Michael Pollak,
    • John A. Porco, Jr.,
    • Julie St-Pierre,
    • Jerry Pelletier,
    • Ola Larsson,
    • and Ivan Topisirovic
    Genome Res. May 2016 26: 636-648; Published in Advance March 16, 2016, doi:10.1101/gr.197566.115
    .... 2014; Wolfe et al. 2014; Modelska et al. 2015). In yeast, Ded1 (the ortholog of DDX3X in mammals), rather than EIF4A, seems to act as a major helicase that resolves secondary 5′ UTR structures (Sen et al. 2015). Accordingly, in yeast, changes in EIF4A activity uniformly affect translation of most mRNAs...
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