Searching journal content for articles similar to Seitz et al. 14 (9): 1741.

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  1. Research: Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control
    • Miguel L. Soares,
    • Carol A. Edwards,
    • Frances L. Dearden,
    • Sacri R. Ferrón,
    • Scott Curran,
    • Jennifer A. Corish,
    • Rebecca C. Rancourt,
    • Sarah E. Allen,
    • Marika Charalambous,
    • Malcolm A. Ferguson-Smith,
    • Willem Rens,
    • David J. Adams,
    • and Anne C. Ferguson-Smith
    Genome Res. March 2018 28: 345-356; Published in Advance January 24, 2018, doi:10.1101/gr.221366.117
    ...the consequences of the deletion on regional control of gene expression and imprinting.ResultsLarge L1 arrays are associated with tandem gene clusters in the mammalian To determine where in the mouse stretches of dense LINE content reside, regions containing >70% LINEs of >100 kb length were cataloged. Sixty...
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  2. Letter: Epigenetic profiling at mouse imprinted gene clusters reveals novel epigenetic and genetic features at differentially methylated regions
    • Scott V. Dindot,
    • Richard Person,
    • Mark Strivens,
    • Rejinaldo Garcia,
    • and Arthur L. Beaudet
    Genome Res. August 2009 19: 1374-1383; Published in Advance June 19, 2009, doi:10.1101/gr.089185.108
    ...). Currently there are about 100 known imprinted genes in the mouse, including protein coding genes, noncoding RNA transcripts, and micro-RNAs (www.har.mrc.ac.uk/research/ genomic_imprinting). Most of these genes are found in clusters, and in most cases the domains harbor a CpG rich imprinting control region...
  3. Research: Assessing the effect of the CLPG mutation on the microRNA catalog of skeletal muscle using high-throughput sequencing
    • Florian Caiment,
    • Carole Charlier,
    • Tracy Hadfield,
    • Noelle Cockett,
    • Michel Georges,
    • and Denis Baurain
    Genome Res. December 2010 20: 1651-1662; Published in Advance October 13, 2010, doi:10.1101/gr.108787.110
    ...the DLK1–GTL2 domain in skeletal muscle of eight sheep sorted by CLPG genotype (gray: +/+; blue: +Mat/CLPGPat; red: CLPGMat/+Pat; purple: CLPG/CLPG). Error bars correspond to 1.96 3 the standard error of the estimate. A microRNA catalog of callipyge skeletal muscle Genome Research 1655 www..org +Mat...
  4. Review: The superpowers of imprinting control regions
    • Bertille Montibus,
    • Franck Court,
    • and Philippe Arnaud
    Genome Res. January 2026 36: 1-19; Published in Advance December 10, 2025, doi:10.1101/gr.281215.125
    ...conserved genomic clusters, which contain two or more maternally and paternally expressed genes in large regions of up to several megabases in size (Table 1; Fig. 1).View larger version: In this window In a new window Figure 1. Schematic representation of the genomic organization of the 10 largest imprinted...
  5. ARTICLE: Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome
    • Timothy Ravasi,
    • Harukazu Suzuki,
    • Ken C. Pang,
    • Shintaro Katayama,
    • Masaaki Furuno,
    • Rie Okunishi,
    • Shiro Fukuda,
    • Kelin Ru,
    • Martin C. Frith,
    • M. Milena Gongora,
    • Sean M. Grimmond,
    • David A. Hume,
    • Yoshihide Hayashizaki,
    • and John S. Mattick
    Genome Res. January 2006 16: 11-19; Published in Advance December 12, 2005, doi:10.1101/gr.4200206
    ...RNAs, termed microRNAs, have also been shown to be involved in developmental processes in both plants and animals, as well as implicated in disease ( Carrington and Ambros 2003 ; Mattick and Makunin 2005 ). Recent evidence suggests that these microRNAs are derived from the introns of capped and polyadenylated...
  6. Research: Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation
    • Clara Y. Cheong,
    • Keefe Chng,
    • Shilen Ng,
    • Siew Boom Chew,
    • Louiza Chan,
    • and Anne C. Ferguson-Smith
    Genome Res. May 2015 25: 611-623; Published in Advance April 10, 2015, doi:10.1101/gr.183301.114
    ...- and tissue-specific domains of imprinted expression exist. Using the cynomolgus macaque ( Macaca fascicularis ) to assess primate-specific imprinting, we present a comprehensive view of tissue-specific imprinted expression and DNA methylation at established imprinted gene clusters. For example, like mouse...
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  7. Research: Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment
    • Franck Court,
    • Chiharu Tayama,
    • Valeria Romanelli,
    • Alex Martin-Trujillo,
    • Isabel Iglesias-Platas,
    • Kohji Okamura,
    • Naoko Sugahara,
    • Carlos Simón,
    • Harry Moore,
    • Julie V. Harness,
    • Hans Keirstead,
    • Jose Vicente Sanchez-Mut,
    • Eisuke Kaneki,
    • Pablo Lapunzina,
    • Hidenobu Soejima,
    • Norio Wake,
    • Manel Esteller,
    • Tsutomu Ogata,
    • Kenichiro Hata,
    • Kazuhiko Nakabayashi,
    • and David Monk
    Genome Res. April 2014 24: 554-569; Published in Advance January 8, 2014, doi:10.1101/gr.164913.113
    ...Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Catalonia, Spain; 14 Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan Abstract Differential methylation between the two alleles of a gene has been observed in imprinted regions, where...
  8. Research: Discovery of hundreds of mirtrons in mouse and human small RNA data
    • Erik Ladewig,
    • Katsutomo Okamura,
    • Alex S. Flynt,
    • Jakub O. Westholm,
    • and Eric C. Lai
    Genome Res. September 2012 22: 1634-1645; doi:10.1101/gr.133553.111
    ...mammalian locusMir668 began with the canonical splice donor ‘‘GUAAGU’’ (Fig. 2A).Mir668 is located in a supercluster of many tens of miRNAs (Seitz et al. 2004), many of which are associated with a maternally imprinted primary transcript cloned from mouse termed Mirg (‘‘miRNA containing gene’’). Indeed, mmu...
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  9. PERSPECTIVE: Origin of phenotypes: Genes and transcripts
    • Thomas R. Gingeras
    Genome Res. June 2007 17: 682-690; doi:10.1101/gr.6525007
    ...In a new window Figure 2. Transcriptional complexity of a gene. Hypothetical gene cluster with detailed zoom-in for highlighted gene demonstrates that a single gene can have multiple transcriptional start sites (TSSs) as well as many interleaved coding and noncoding transcripts. Exons are shown as red...
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