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  1. ...) Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature. Genome Res. 12 : 203 – 214 . ↵ Schug J. , Diskin S. , Mazzarelli J. , Brunk B.P. , Stoeckert C.J. , Jr. ( 2002 ) Predicting gene ontology functions from ProDom and CDD protein domains. Genome Res. 12 : 648...
  2. ....K. , Gubler U. ( 1992 ) Cloning and expression of murine IL-12. J. Immunol. 148 : 3433 – 3440 . ↵ Schug J. , Diskin S. , Mazzarelli J. , Brunk B.P. , Stoeckert C.J. , Jr. ( 2002 ) Predicting gene ontology functions from ProDom and CDD protein domains. Genome Res. 12 : 648 – 655 . ↵ Shields D.C. , Harmon D...
  3. ...% of assemblies have similarities to ProDom (available at http://prodes.toulouse.inra.fr/prodom/doc/prodom.html ), whereas ∼10%–12% of the assemblies have significant similarities to Conserved Domain Database entries (CDD; available at http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml ) with a conservative...
  4. ...for the domain definition. Homologs The Homologs section displays all BLASTp hits to other genes in the MicrobesOnline database as well as hits to the KEGG ( Kanehisa 2002 ) and SWISS-PROT ( Boeckmann et al. 2003 ) databases, and RPS-BLAST hits to the COG families in the CDD database (Marchler-Bauer et al. 2002...
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  5. ....g., functional assignments based on Gene Ontologies; Ashburner et al. 2000 ; The Gene Ontology Consortium 2001 ; Schug et al. 2002 ), and a multiple sequence alignment of the group members generated using CLUSTALW ( Thompson et al. 1994 ). The graphical representation can be customized to selectively show two...
  6. ...and associated tools for efficient recognition of domains in new proteins have been developed, including Pfam ( Bateman et al. 2002 ), SMART ( Schultz et al. 1998 ), PRODOM ( Servant et al. 2002 ), CDD ( Marchler-Bauer et al. 2003 ), INTERPRO ( Mulder et al. 2003 ), DALI ( Holm and Sander 1998 ), CATH ( Orengo...
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