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  1. ...the heterogeneous transcriptional coregulation of gene programs within specific cellular and spatial contexts, such as cell types, cell states, disease conditions, and spatial locations. This approach enables DeCEP to integrate a priori functional gene lists and directed graphs to construct functional networks...
  2. ..., and the affected genes. The signaling and regulatory components of our networks are linked via a set of common transcription factors that serve as targets in the signaling network and as regulators of the transcriptional response network. Detailed case studies of stress responses in budding yeast demonstrate...
  3. ...author: akimitsu@ric.u-tokyo.ac.jpAbstractGene expression is determined by a balance between RNA synthesis and RNA degradation. To elucidate the underlying regulatory mechanisms and principles of this, simultaneous measurements of RNA synthesis and degradation are required. Here, we report...
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