Searching journal content for articles similar to Schmidt et al. 25 (9): 1281.

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  1. Research: Binding of nuclear factor κB to noncanonical consensus sites reveals its multimodal role during the early inflammatory response
    • Petros Kolovos,
    • Theodore Georgomanolis,
    • Anna Koeferle,
    • Joshua D. Larkin,
    • Lilija Brant,
    • Miloš Nikolicć,
    • Eduardo G. Gusmao,
    • Anne Zirkel,
    • Tobias A. Knoch,
    • Wilfred F. van Ijcken,
    • Peter R. Cook,
    • Ivan G. Costa,
    • Frank G. Grosveld,
    • and Argyris Papantonis
    Genome Res. November 2016 26: 1478-1489; Published in Advance September 15, 2016, doi:10.1101/gr.210005.116
    ...are predominantly associated with genes upregulated upon stimulation) (Supplemental Fig. S2H). Collectively, these data point to a TNF-induced, RELA-mediated, repressive mechanism. ChIA-PET analysis reveals differential functions of RELA-bound enhancers Binding of NF-κB at already-active enhancers along the linear...
  2. Research: Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-kB binding
    • Liangxi Wang,
    • Tiegh Taylor,
    • Kumaragurubaran Rathnakumar,
    • Nadiya Khyzha,
    • Minggao Liang,
    • Azad Alizada,
    • Laura F. Campitelli,
    • Sara E. Pour,
    • Zain M. Patel,
    • Lina Antounians,
    • Ian C. Tobias,
    • Huayun Hou,
    • Timothy R. Hughes,
    • Sushmita Roy,
    • Jennifer A. Mitchell,
    • Jason E. Fish,
    • and Michael D. Wilson
    Genome Res. July 2025 35: 1544-1559; Published in Advance June 6, 2025, doi:10.1101/gr.280357.124
    ...find human RELA-bound MER81 instances are enriched for the interferon gamma pathway and demonstrate that one RELA-bound MER81 element can control the TNF-induced expression of interferon gamma receptor 2 (IFNGR2). Using ancestral reconstructions, we find that RELA containing MER81 instances rapidly...
  3. Method: Models of human core transcriptional regulatory circuitries
    • Violaine Saint-André,
    • Alexander J. Federation,
    • Charles Y. Lin,
    • Brian J. Abraham,
    • Jessica Reddy,
    • Tong Ihn Lee,
    • James E. Bradner,
    • and Richard A. Young
    Genome Res. March 2016 26: 385-396; Published in Advance February 3, 2016, doi:10.1101/gr.197590.115
    ...the logic outlined in Figure 1. Detailed studies of the transcriptional control of cell identity in ESCs and a few other cell types have shown that core TFs have three properties. Core TFs are encoded by genes associated with super-enhancers (Hnisz et al. 2013; Whyte et al. 2013), bind the SEs associated...
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